Read the fine print: Biomolecular binding events can be counted with a readout system based on compact disc (CD) pickup technology. An immunoassay of C-reactive protein was performed by microcontact printing of antibodies onto a support, autometallography, and imaging by a CD reader mounted on an optical microscope (see picture). The dynamic range was four orders of magnitude with a detection limit of 1 pM.
|Translated title of the contribution||Measuring Biomolecular Binding Events with a Compact Disc Player Device|
|Number of pages||4|
|Journal||Angewandte Chemie - International Edition|
|Early online date||21 Dec 2005|
|Publication status||Published - Dec 2005|
Bibliographical notePublisher: Wiley
Lange, SA., Roth, G., Wittemann, S., Lacoste, T., Vetter, A., Grässle, J., Kopta, S., Kolleck, M., Breitinger, B., Wick, M., Hoerber, JKH., Dubel, S., & Bernard, A. (2005). Measuring Biomolecular Binding Events with a Compact Disc Player Device. Angewandte Chemie - International Edition, 45(2), 270-273. https://doi.org/10.1002/anie.200501243