Measuring Biomolecular Binding Events with a Compact Disc Player Device

SA Lange; G Roth; S Wittemann; T Lacoste; A Vetter; J Grässle; S Kopta; M Kolleck; B Breitinger; M Wick; JKH Hoerber; S Dubel; A Bernard

doi:10.1002/anie.200501243

Measuring Biomolecular Binding Events with a Compact Disc Player Device

SA Lange
, G Roth
, S Wittemann
, T Lacoste
, A Vetter
, J Grässle
, S Kopta
, M Kolleck
, B Breitinger
, M Wick
, JKH Hoerber
, S Dubel
, A Bernard

School of Physics

Research output: Contribution to journal › Article (Academic Journal) › peer-review

61 Citations (Scopus)

Abstract

Read the fine print: Biomolecular binding events can be counted with a readout system based on compact disc (CD) pickup technology. An immunoassay of C-reactive protein was performed by microcontact printing of antibodies onto a support, autometallography, and imaging by a CD reader mounted on an optical microscope (see picture). The dynamic range was four orders of magnitude with a detection limit of 1 pM.

Translated title of the contribution	Measuring Biomolecular Binding Events with a Compact Disc Player Device
Original language	English
Pages (from-to)	270-273
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	45
Issue number	2
Early online date	21 Dec 2005
DOIs	https://doi.org/10.1002/anie.200501243
Publication status	Published - Dec 2005

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Publisher: Wiley

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title = "Measuring Biomolecular Binding Events with a Compact Disc Player Device",

abstract = "Read the fine print: Biomolecular binding events can be counted with a readout system based on compact disc (CD) pickup technology. An immunoassay of C-reactive protein was performed by microcontact printing of antibodies onto a support, autometallography, and imaging by a CD reader mounted on an optical microscope (see picture). The dynamic range was four orders of magnitude with a detection limit of 1 pM.",

author = "SA Lange and G Roth and S Wittemann and T Lacoste and A Vetter and J Gr{\"a}ssle and S Kopta and M Kolleck and B Breitinger and M Wick and JKH Hoerber and S Dubel and A Bernard",

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T1 - Measuring Biomolecular Binding Events with a Compact Disc Player Device

AU - Lange, SA

AU - Roth, G

AU - Wittemann, S

AU - Lacoste, T

AU - Vetter, A

AU - Grässle, J

AU - Kopta, S

AU - Kolleck, M

AU - Breitinger, B

AU - Wick, M

AU - Hoerber, JKH

AU - Dubel, S

AU - Bernard, A

N1 - Publisher: Wiley

PY - 2005/12

Y1 - 2005/12

N2 - Read the fine print: Biomolecular binding events can be counted with a readout system based on compact disc (CD) pickup technology. An immunoassay of C-reactive protein was performed by microcontact printing of antibodies onto a support, autometallography, and imaging by a CD reader mounted on an optical microscope (see picture). The dynamic range was four orders of magnitude with a detection limit of 1 pM.

AB - Read the fine print: Biomolecular binding events can be counted with a readout system based on compact disc (CD) pickup technology. An immunoassay of C-reactive protein was performed by microcontact printing of antibodies onto a support, autometallography, and imaging by a CD reader mounted on an optical microscope (see picture). The dynamic range was four orders of magnitude with a detection limit of 1 pM.

U2 - 10.1002/anie.200501243

DO - 10.1002/anie.200501243

M3 - Article (Academic Journal)

SN - 1433-7851

VL - 45

SP - 270

EP - 273

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 2

ER -

Measuring Biomolecular Binding Events with a Compact Disc Player Device

Abstract

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