Mechanisms of antibiotic resistance: QM/MM modeling of the acylation reaction of a class A β-lactamase with benzylpencillin

JC Hermann; C Hensen; L-O Ridder; AJ Mulholland; HD Höltje

doi:10.1021/ja044210d

Mechanisms of antibiotic resistance: QM/MM modeling of the acylation reaction of a class A β-lactamase with benzylpencillin

JC Hermann, C Hensen, L-O Ridder, AJ Mulholland, HD Höltje

School of Chemistry

Research output: Contribution to journal › Article (Academic Journal) › peer-review

130 Citations (Scopus)

Translated title of the contribution	Mechanisms of antibiotic resistance: QM/MM modeling of the acylation reaction of a class A β-lactamase with benzylpencillin
Original language	English
Pages (from-to)	4454 - 4465
Number of pages	12
Journal	Journal of the American Chemical Society
Volume	127 (12)
DOIs	https://doi.org/10.1021/ja044210d
Publication status	Published - Mar 2005

Bibliographical note

Publisher: American Chemical Society

Research Groups and Themes

Physical & Theoretical

Access to Document

10.1021/ja044210d

http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/2005/127/i12/abs/ja044210d.html

Handle.net

Persistent link

Cite this

@article{31e6ffb5f6ab470980ed32a09c95a0c3,

title = "Mechanisms of antibiotic resistance: QM/MM modeling of the acylation reaction of a class A β-lactamase with benzylpencillin",

author = "JC Hermann and C Hensen and L-O Ridder and AJ Mulholland and HD H{\"o}ltje",

note = "Publisher: American Chemical Society",

year = "2005",

month = mar,

doi = "10.1021/ja044210d",

language = "English",

volume = "127 (12)",

pages = "4454 -- 4465",

journal = "Journal of the American Chemical Society",

issn = "1520-5126",

publisher = "American Chemical Society",

}

TY - JOUR

T1 - Mechanisms of antibiotic resistance: QM/MM modeling of the acylation reaction of a class A β-lactamase with benzylpencillin

AU - Hermann, JC

AU - Hensen, C

AU - Ridder, L-O

AU - Mulholland, AJ

AU - Höltje, HD

N1 - Publisher: American Chemical Society

PY - 2005/3

Y1 - 2005/3

U2 - 10.1021/ja044210d

DO - 10.1021/ja044210d

M3 - Article (Academic Journal)

SN - 1520-5126

VL - 127 (12)

SP - 4454

EP - 4465

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

ER -