Mechano-transduction in osteobastic cells involves strain-regulated, Estrogen Receptor alpha-mediated, control of Insulin-Like Growth Factor (IGF) I receptor sensitivity to ambient IGF, leading to P13-K/AKT dependent, Wnt/LRP5 receptor-independent activation of beta-catenin signaling

A Sunters, VJ Armstrong, G Zaman, RM Kypta, Y Kawano, Lance E Lanyon, J Price

Research output: Contribution to journalArticle (Academic Journal)peer-review

94 Citations (Scopus)
Translated title of the contributionMechano-transduction in osteobastic cells involves strain-regulated, Estrogen Receptor alpha-mediated, control of IGF-IR sensitivity to ambient IGF, leading to P13-K/AKT dependent, Wnt/LRP5 receptor-independent activation of beta-catenin signalling
Original languageEnglish
Pages (from-to)8743 - 8758
Number of pages16
JournalJournal of Biological Chemistry
Volume285
Issue number12
DOIs
Publication statusPublished - Mar 2010

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