TY - JOUR
T1 - Mechanochemical Active Feedback Generates Convergence Extension in Epithelial Tissue
AU - Ioratim-Uba, Aondoyima
AU - Liverpool, Tanniemola B.
AU - Henkes, Silke
PY - 2023/12/7
Y1 - 2023/12/7
N2 - Convergent extension (CE) is a morphogenetic process that occurs during development. It is conserved across many different species, types of tissues, and stages of development [1–4]. During convergent extension, a region of sheetlike (epithelial) tissue elongates in one direction (the long axis) and contracts perpendicular to it. Convergent extension plays a key role in a variety of developmental processes, such as primitive streak formation in chick embryos [5,6] and drosophila germ band extension [7,8] which are important parts of gastrulation. This is the topological inversion process shared by nearly all multicellular animals and some plants [9] that leads to cells taking up their correct positions within the embryo.
AB - Convergent extension (CE) is a morphogenetic process that occurs during development. It is conserved across many different species, types of tissues, and stages of development [1–4]. During convergent extension, a region of sheetlike (epithelial) tissue elongates in one direction (the long axis) and contracts perpendicular to it. Convergent extension plays a key role in a variety of developmental processes, such as primitive streak formation in chick embryos [5,6] and drosophila germ band extension [7,8] which are important parts of gastrulation. This is the topological inversion process shared by nearly all multicellular animals and some plants [9] that leads to cells taking up their correct positions within the embryo.
U2 - 10.1103/PhysRevLett.131.238301
DO - 10.1103/PhysRevLett.131.238301
M3 - Article (Academic Journal)
C2 - 38134807
SN - 0031-9007
VL - 131
JO - Physical Review Letters
JF - Physical Review Letters
M1 - 238301
ER -