Metformin and Abdominal Aortic Aneurysm

Robert Hinchliffe

doi:10.1016/j.ejvs.2017.08.016

Metformin and Abdominal Aortic Aneurysm

Robert Hinchliffe

Research output: Contribution to journal › Editorial (Academic Journal) › peer-review

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Abstract

Recently published data from a number of sources appear to suggest that the oral hypoglycaemic agent metformin may prevent abdominal aortic aneurysm (AAA) development, attenuate growth, and perhaps even prevent rupture. Previous studies have hinted that hypoglycaemic agents might reduce AAA expansion.1 The latest data, specific to metformin are compelling. Metformin is a biologically plausible drug since it has a wide range of effects on inflammation and metabolism. Potentially exciting observations remain preliminary and should be interpreted with caution.

Original language	English
Pages (from-to)	679-680
Number of pages	2
Journal	European Journal of Vascular and Endovascular Surgery
Volume	54
Issue number	6
Early online date	5 Oct 2017
DOIs	https://doi.org/10.1016/j.ejvs.2017.08.016
Publication status	Published - Dec 2017

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Centre for Surgical Research

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This is the author accepted manuscript (AAM). The final published version (version of record) is available online via Elsevier at https://www.sciencedirect.com/science/article/pii/S107858841730518X?via%3Dihub. Please refer to any applicable terms of use of the publisher.
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title = "Metformin and Abdominal Aortic Aneurysm",

abstract = "Recently published data from a number of sources appear to suggest that the oral hypoglycaemic agent metformin may prevent abdominal aortic aneurysm (AAA) development, attenuate growth, and perhaps even prevent rupture. Previous studies have hinted that hypoglycaemic agents might reduce AAA expansion.1 The latest data, specific to metformin are compelling. Metformin is a biologically plausible drug since it has a wide range of effects on inflammation and metabolism. Potentially exciting observations remain preliminary and should be interpreted with caution.",

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AU - Hinchliffe, Robert

PY - 2017/12

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AB - Recently published data from a number of sources appear to suggest that the oral hypoglycaemic agent metformin may prevent abdominal aortic aneurysm (AAA) development, attenuate growth, and perhaps even prevent rupture. Previous studies have hinted that hypoglycaemic agents might reduce AAA expansion.1 The latest data, specific to metformin are compelling. Metformin is a biologically plausible drug since it has a wide range of effects on inflammation and metabolism. Potentially exciting observations remain preliminary and should be interpreted with caution.

UR - https://www.scopus.com/pages/publications/85030653235

U2 - 10.1016/j.ejvs.2017.08.016

DO - 10.1016/j.ejvs.2017.08.016

M3 - Editorial (Academic Journal)

C2 - 28988609

AN - SCOPUS:85030653235

SN - 1078-5884

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JO - European Journal of Vascular and Endovascular Surgery

JF - European Journal of Vascular and Endovascular Surgery

IS - 6

ER -

Metformin and Abdominal Aortic Aneurysm

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