Projects per year
Methods: Systematic reviews of the most common conditions requiring unplanned admission and treat-ment managed by general surgeons were eligible for inclusion. The Centre for Reviews and D issemi-nation databases were searched to April 2014. The number and type (randomized or non-randomized) of included studies and patients were extracted and summarized. The total number of unique stud-ies was recorded for each condition. The nature of the interventions (surgical, non-surgical invasive ornon-invasive) was documented. The quality of reviews was assessed using the AMSTAR checklist.
Results: The 106 included reviews focused mainly on bowel conditions (42), appendicitis (40) andgallstone disease (17). Fifty-one (48⋅1 per cent) included RCTs alone, 79 (74⋅5 per cent) included at least one RCT and 25 (23⋅6 per cent) summarized non-randomized evidence alone. Reviews included727 unique studies, of which 30⋅3 per cent were RCTs. Sixty-ve reviews compared different types of surgical intervention and 27 summarized trials of surgical versus non-surgical interventions. Fifty-seven reviews (53⋅8 per cent) were rated as low risk of bias.
Conclusion: This overview of reviews highlights the need for more and better research in this field.
- Centre for Surgical Research