MicroRNA annotation of plant genomes - Do it right or not at all

Richard S. Taylor*, James E. Tarver, Alireza Foroozani, Philip C J Donoghue

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

18 Citations (Scopus)
322 Downloads (Pure)

Abstract

MicroRNAs are non-coding regulators of gene expression and key factors in development, disease, and targets for bioengineering. Consequently, microRNAs have become essential elements of already burgeoning draft plant genome descriptions where their annotation is often particularly poor, contributing unduly to the corruption of public databases. Using the Citrus sinensis as an example, we highlight and review common failings of miRNAome annotations. Understanding and exploiting the role of miRNAs in plant biology will be stymied unless the research community acts decisively to improve the accuracy of miRNAome annotations. We encourage genome annotation teams to do it right or not at all.
Original languageEnglish
Article number1600113
Number of pages6
JournalBioEssays
Volume39
Issue number2
Early online date5 Jan 2017
DOIs
Publication statusPublished - Feb 2017

Keywords

  • plant
  • genome
  • annotation
  • microRNA
  • mis-annotation
  • miRBase
  • Citrus
  • evolution

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