Mild heating and reduction of bladder spontaneous contractions

Darryl Kitney; Rita Jabr; Bahareh Vahabi; Christopher Fry

doi:10.1111/bju.13933

Mild heating and reduction of bladder spontaneous contractions

Darryl Kitney, Rita Jabr, Bahareh Vahabi, Christopher Fry

School of Physiology, Pharmacology & Neuroscience

Research output: Contribution to journal › Article (Academic Journal) › peer-review

3 Citations (Scopus)

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Abstract

The urinary bladder generates spontaneous contractile activity (SA) to maintain bladder wall tone but remains compliant during filling. SA is greater in isolated preparations from patients with overactive bladder (OAB) and may underlie the associated symptoms. Due to significant refractoriness and adverse side-effects of drug-based therapies, new approaches to alleviate the symptoms of OAB are desirable. One approach may be through mild heating of the bladder wall.

Original language	English
Number of pages	7
Journal	BJU International
Early online date	20 Jul 2017
DOIs	https://doi.org/10.1111/bju.13933
Publication status	E-pub ahead of print - 20 Jul 2017

Bibliographical note

31-May-17

Keywords

heating
overactive bladder
spontaneous contractions

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10.1111/bju.13933

Full-text PDF (accepted author manuscript)
This is the author accepted manuscript (AAM). The final published version (version of record) is available online via Wiley at http://onlinelibrary.wiley.com/doi/10.1111/bju.13933/abstract. Please refer to any applicable terms of use of the publisher.
Accepted author manuscript, 663 KBLicence: CC BY-NC

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AB - The urinary bladder generates spontaneous contractile activity (SA) to maintain bladder wall tone but remains compliant during filling. SA is greater in isolated preparations from patients with overactive bladder (OAB) and may underlie the associated symptoms. Due to significant refractoriness and adverse side-effects of drug-based therapies, new approaches to alleviate the symptoms of OAB are desirable. One approach may be through mild heating of the bladder wall.

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Mild heating and reduction of bladder spontaneous contractions

Abstract

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Keywords

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