Mitral Valve Repair or Replacement for Ischaemic Mitral Regurgitation: A Systematic Review

C Rao; MO Murphy; S Saso; D Pandis; J Grapsa; P Nihoyannopoulos; BC Reeves; T Athanasiou

doi:10.1016/j.hlc.2011.03.012

Mitral Valve Repair or Replacement for Ischaemic Mitral Regurgitation: A Systematic Review

C Rao, MO Murphy, S Saso, D Pandis, J Grapsa, P Nihoyannopoulos, BC Reeves, T Athanasiou

Research output: Contribution to journal › Article (Academic Journal) › peer-review

9 Citations (Scopus)

Abstract

A literature review was undertaken according to Cochrane guidelines to identify whether mitral valve repair (MV-Repair) or replacement (MV-Replacement) is more effective in patients with moderate to severe ischaemic mitral regurgitation. The literature suggests MV-Repair may have improved 30-day mortality and long-term survival. All 12 studies identified, however, were non-randomised, retrospective, and at significant risk of bias due to heterogeneous surgical techniques and mismatched patient characteristics. Data describing the need for reoperation were not sufficiently well reported to analyse. Functional outcomes and health-related quality of life were not reported. In conclusion, high-quality randomised comparison of MV-Repair and MV-Replacement is urgently needed.

Translated title of the contribution	Mitral Valve Repair or Replacement for Ischaemic Mitral Regurgitation: A Systematic Review
Original language	English
Pages (from-to)	555 - 565
Number of pages	11
Journal	Heart, Lung and Circulation
DOIs	https://doi.org/10.1016/j.hlc.2011.03.012
Publication status	Published - Sep 2011

Structured keywords

BTC (Bristol Trials Centre)

Access to Document

10.1016/j.hlc.2011.03.012

http://www.sciencedirect.com/science/article/pii/S1443950611001387

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Cite this

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title = "Mitral Valve Repair or Replacement for Ischaemic Mitral Regurgitation: A Systematic Review",

abstract = "A literature review was undertaken according to Cochrane guidelines to identify whether mitral valve repair (MV-Repair) or replacement (MV-Replacement) is more effective in patients with moderate to severe ischaemic mitral regurgitation. The literature suggests MV-Repair may have improved 30-day mortality and long-term survival. All 12 studies identified, however, were non-randomised, retrospective, and at significant risk of bias due to heterogeneous surgical techniques and mismatched patient characteristics. Data describing the need for reoperation were not sufficiently well reported to analyse. Functional outcomes and health-related quality of life were not reported. In conclusion, high-quality randomised comparison of MV-Repair and MV-Replacement is urgently needed.",

author = "C Rao and MO Murphy and S Saso and D Pandis and J Grapsa and P Nihoyannopoulos and BC Reeves and T Athanasiou",

year = "2011",

month = sep,

doi = "10.1016/j.hlc.2011.03.012",

language = "English",

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journal = "Heart, Lung and Circulation",

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T1 - Mitral Valve Repair or Replacement for Ischaemic Mitral Regurgitation: A Systematic Review

AU - Rao, C

AU - Murphy, MO

AU - Saso, S

AU - Pandis, D

AU - Grapsa, J

AU - Nihoyannopoulos, P

AU - Reeves, BC

AU - Athanasiou, T

PY - 2011/9

Y1 - 2011/9

N2 - A literature review was undertaken according to Cochrane guidelines to identify whether mitral valve repair (MV-Repair) or replacement (MV-Replacement) is more effective in patients with moderate to severe ischaemic mitral regurgitation. The literature suggests MV-Repair may have improved 30-day mortality and long-term survival. All 12 studies identified, however, were non-randomised, retrospective, and at significant risk of bias due to heterogeneous surgical techniques and mismatched patient characteristics. Data describing the need for reoperation were not sufficiently well reported to analyse. Functional outcomes and health-related quality of life were not reported. In conclusion, high-quality randomised comparison of MV-Repair and MV-Replacement is urgently needed.

AB - A literature review was undertaken according to Cochrane guidelines to identify whether mitral valve repair (MV-Repair) or replacement (MV-Replacement) is more effective in patients with moderate to severe ischaemic mitral regurgitation. The literature suggests MV-Repair may have improved 30-day mortality and long-term survival. All 12 studies identified, however, were non-randomised, retrospective, and at significant risk of bias due to heterogeneous surgical techniques and mismatched patient characteristics. Data describing the need for reoperation were not sufficiently well reported to analyse. Functional outcomes and health-related quality of life were not reported. In conclusion, high-quality randomised comparison of MV-Repair and MV-Replacement is urgently needed.

U2 - 10.1016/j.hlc.2011.03.012

DO - 10.1016/j.hlc.2011.03.012

M3 - Article (Academic Journal)

C2 - 21497550

SP - 555

EP - 565

JO - Heart, Lung and Circulation

JF - Heart, Lung and Circulation

SN - 1443-9506

ER -