Abstract
Development of a vaccine against herpes simplex virus (HSV) is an important goal for global sexual and reproductive health. In order to more precisely define the health and economic burden of HSV infection and the theoretical impact and cost-effectiveness of an HSV vaccine, in 2015 the World Health Organization convened an expert consultation meeting on HSV vaccine impact modelling. The experts reviewed existing model-based estimates and dynamic models of HSV infection to outline critical future modelling needs to inform development of a comprehensive business case and preferred product characteristics for an HSV vaccine. This article summarizes key findings and discussions from the meeting on modelling needs related to HSV burden, costs, and vaccine impact, essential data needs to carry out those models, and important model components and parameters.
Original language | English |
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Pages (from-to) | 7336-7345 |
Number of pages | 10 |
Journal | Vaccine |
Volume | 37 |
Issue number | 50 |
Early online date | 21 Jun 2017 |
DOIs |
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Publication status | Published - 28 Nov 2019 |
Keywords
- Herpes simplex virus
- Sexually transmitted infections
- HSV vaccines
- Modelling
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Dr Katharine J Looker
- Bristol Medical School (PHS) - NIHR Research Fellow in Mathematical Epidemiology of Infectious Diseases
- Bristol Population Health Science Institute
- Infection and Immunity
Person: Academic , Member