Molecular determinants of hERG potassium channel inhibition by disopyramide

Medicine and Dentistry

• Disopyramide 100%
• Potassium Channel 100%
• IC50 83%
• Tail 33%
• Helix 33%
• Long QT Syndrome 33%
• Base 16%
• Potassium Current 16%
• QT Prolongation 16%
• Potassium Ion 16%
• HEK 293 Cells 16%
• Alanine 16%
• Homology Modeling 16%
• Antiarrhythmic Agent 16%
• Short QT Syndrome 16%
• Binding Energy 16%
• Whole Cell 16%

Biochemistry, Genetics and Molecular Biology

• Potassium Channel 100%
• Disopyramide 100%
• IC50 83%
• Long QT Syndrome 33%
• Homology Modeling 16%
• Whole Cell 16%
• Electric Potential 16%
• Potassium Current 16%
• QT Interval 16%
• HEK 293 Cells 16%
• Short QT Syndrome 16%
• Antiarrhythmic Agent 16%
• Binding Energy 16%
• Alanine 16%

Agricultural and Biological Sciences

• Potassium Channel 100%
• Tail 100%
• HEK 293 Cells 50%
• Binding Energy 50%
• Alanine 50%