Molecular targets and pharmacodynamics for bactericidal and bacteriostatic activity

Pavani Cherukupally; Claudio Lourenco; Cher Farrugia; Diana Marcela Castillo; Maja Sabalic-Schoener

doi:10.1016/B978-0-12-823994-0.00009-8

Molecular targets and pharmacodynamics for bactericidal and bacteriostatic activity

Pavani Cherukupally, Claudio Lourenco, Cher Farrugia, Diana Marcela Castillo, Maja Sabalic-Schoener

Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book

Abstract

The use of antimicrobial nanoparticles for antimicrobial drug delivery is a promising area of research, and there is evidence to suggest that these particles can effectively deliver antimicrobials or inhibit microbial growth while overcoming antimicrobial resistance mechanisms. Nanotechnology in preventive dentistry and the treatment of common dental conditions has been used as an example to illustrate the ample potential of these materials. Emerging Artificial Intelligence applications are also reviewed. Pharmacodynamics and pharmacokinetics of microbial nanomaterials have been discussed, as well as their safety. More research is needed before antimicrobial nanoparticles can be applied routinely in clinical care.

Original language	English
Title of host publication	Nanotechnology Tools for Infection Control
Subtitle of host publication	Scanning New Horizons on Next-Generation Therapies to Eradicate Pathogens and Fight Drug Resistance
Publisher	Elsevier
Pages	209-246
Number of pages	38
ISBN (Electronic)	9780128239940
ISBN (Print)	9780128239957
DOIs	https://doi.org/10.1016/B978-0-12-823994-0.00009-8
Publication status	Published - 1 Jan 2024

Bibliographical note

Publisher Copyright:
© 2025 Elsevier Inc. All rights reserved.

Keywords

Anti-infective agents
Antimicrobial agents
Nanomaterials
Nanoparticles
Nanotechnology

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10.1016/B978-0-12-823994-0.00009-8

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Cherukupally, P., Lourenco, C., Farrugia, C., Castillo, D. M., & Sabalic-Schoener, M. (2024). Molecular targets and pharmacodynamics for bactericidal and bacteriostatic activity. In Nanotechnology Tools for Infection Control: Scanning New Horizons on Next-Generation Therapies to Eradicate Pathogens and Fight Drug Resistance (pp. 209-246). Elsevier. https://doi.org/10.1016/B978-0-12-823994-0.00009-8

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Cherukupally, P, Lourenco, C, Farrugia, C, Castillo, DM & Sabalic-Schoener, M 2024, Molecular targets and pharmacodynamics for bactericidal and bacteriostatic activity. in Nanotechnology Tools for Infection Control: Scanning New Horizons on Next-Generation Therapies to Eradicate Pathogens and Fight Drug Resistance. Elsevier, pp. 209-246. https://doi.org/10.1016/B978-0-12-823994-0.00009-8

Molecular targets and pharmacodynamics for bactericidal and bacteriostatic activity. / Cherukupally, Pavani; Lourenco, Claudio; Farrugia, Cher et al.
Nanotechnology Tools for Infection Control: Scanning New Horizons on Next-Generation Therapies to Eradicate Pathogens and Fight Drug Resistance. Elsevier, 2024. p. 209-246.

Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book

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T1 - Molecular targets and pharmacodynamics for bactericidal and bacteriostatic activity

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SN - 9780128239957

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EP - 246

BT - Nanotechnology Tools for Infection Control

PB - Elsevier

ER -

Cherukupally P, Lourenco C, Farrugia C, Castillo DM, Sabalic-Schoener M. Molecular targets and pharmacodynamics for bactericidal and bacteriostatic activity. In Nanotechnology Tools for Infection Control: Scanning New Horizons on Next-Generation Therapies to Eradicate Pathogens and Fight Drug Resistance. Elsevier. 2024. p. 209-246 doi: 10.1016/B978-0-12-823994-0.00009-8

Molecular targets and pharmacodynamics for bactericidal and bacteriostatic activity

Abstract

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