mTORC2 Protein-mediated Protein Kinase B (Akt) Serine 473 Phosphorylation Is Not Required for Akt1 Activity in Human Platelets

Biochemistry, Genetics and Molecular Biology

• Kinase 100%
• Phosphotransferase 100%
• Protein Kinase B 100%
• Platelet 100%
• Serine 100%
• Signal Transduction 50%
• Small Molecule 50%
• Mammalian Target of Rapamycin 50%
• Adenosine Triphosphate 50%
• Cell Proliferation 50%
• Thrombocyte Function 50%
• Cell Metabolism 50%
• IC50 50%
• Mitogen-Activated Protein Kinase 50%
• GSK-3 50%
• Cell Survival 50%
• Mammalian Target of Rapamycin Complex 2 50%
• Thrombin 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Serine 100%
• Protein Kinase B 100%
• 2 (4 Amino 1 Isopropyl 1h pyrazolo[3,4 D]pyrimidin 3 Yl) 1h Indol 5 Ol 100%
• Phosphotransferase 40%
• Glycogen Synthase Kinase 20%
• Adenosine Triphosphate 20%
• IC50 20%
• Rapamycin 20%
• Thrombin 20%
• Mammalian Target of Rapamycin Complex 2 20%
• Mammalian Target of Rapamycin Inhibitor 20%