Muscle insulin-like growth factor status, body composition, and functional capacity in hemodialysis patients

Jamie H Macdonald, Mysore K Phanish, Samuele M Marcora, Mahdi Jibani, Lionel L O Bloodworth, Jeffrey M P Holly, Andrew B Lemmey

Research output: Contribution to journalArticle (Academic Journal)

22 Citations (Scopus)

Abstract

Hemodialysis (HD) patients typically have reduced muscle mass and diminished functional capacity. The role of the muscle insulin-like growth factors (IGFs), a principal anabolic system that is involved in protein synthesis and that has downregulation that is implicated in muscle loss in animal models of uremia, has previously not been assessed in vivo in HD patients.
Original languageEnglish
Pages (from-to)248-52
Number of pages5
JournalJournal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation
Volume14
Issue number4
Publication statusPublished - 2004

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