Nanowire Chemical/Biological Sensors: Status and a Roadmap for the Future

John F. Fennell, Sophie F. Liu, Joseph M. Azzarelli, Jonathan G. Weis, S. Rochat, Katherine A. Mirica, Jens B. Ravnsbaek, Timothy M. Swager

Research output: Contribution to journalArticle (Academic Journal)peer-review

Abstract

Chemiresistive sensors are becoming increasingly important as they offer an inexpensive option to conventional analytical instrumentation, they can be readily integrated into electronic devices, and they have low power requirements. Nanowires (NWs) are a major theme in chemosensor development. High surface area, interwire junctions, and restricted conduction pathways give intrinsically high sensitivity and new mechanisms to transduce the binding or action of analytes. This Review details the status of NW chemosensors with selected examples from the literature. We begin by proposing a principle for understanding electrical transport and transduction mechanisms in NW sensors. Next, we offer the reader a review of device performance parameters. Then, we consider the different NW types followed by a summary of NW assembly and different device platform architectures. Subsequently, we discuss NW functionalization strategies. Finally, we propose future developments in NW sensing to address selectivity, sensor drift, sensitivity, response analysis, and emerging applications.
Original languageEnglish
Pages (from-to)1266-1281
JournalAngewandte Chemie - International Edition
Volume55
Issue number4
Early online date11 Dec 2015
DOIs
Publication statusPublished - 22 Jan 2016

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