TY - JOUR
T1 - Neonatal ECMO study of temperature (NEST)
T2 - a randomized controlled trial
AU - Field, David
AU - Juszczak, Ed
AU - Linsell, Louise
AU - Azzopardi, Denis
AU - Cowan, Frances
AU - Marlow, Neil
AU - Edwards, David
AU - NEST Study Collaborative Group
AU - Thoresen, Marianne
PY - 2013/11
Y1 - 2013/11
N2 - Despite evidence to support the use of extracorporeal membrane oxygenation (ECMO) in defined groups of newborn infants, rates of impairment among survivors remain high. Therapeutic hypothermia has been shown to provide neuroprotection in mature infants exposed to perinatal asphyxia. We hypothesized that therapeutic hypothermia during ECMO would reduce the proportion of infants with brain injury, and thus later impairment.
AB - Despite evidence to support the use of extracorporeal membrane oxygenation (ECMO) in defined groups of newborn infants, rates of impairment among survivors remain high. Therapeutic hypothermia has been shown to provide neuroprotection in mature infants exposed to perinatal asphyxia. We hypothesized that therapeutic hypothermia during ECMO would reduce the proportion of infants with brain injury, and thus later impairment.
U2 - 10.1542/peds.2013-1754
DO - 10.1542/peds.2013-1754
M3 - Article (Academic Journal)
C2 - 24144703
SN - 0031-4005
VL - 132
SP - e1247-56
JO - Pediatrics
JF - Pediatrics
IS - 5
ER -