Neonatal ECMO study of temperature (NEST): a randomized controlled trial

David Field, Ed Juszczak, Louise Linsell, Denis Azzopardi, Frances Cowan, Neil Marlow, David Edwards, NEST Study Collaborative Group, Marianne Thoresen

Research output: Contribution to journalArticle (Academic Journal)peer-review

32 Citations (Scopus)


Despite evidence to support the use of extracorporeal membrane oxygenation (ECMO) in defined groups of newborn infants, rates of impairment among survivors remain high. Therapeutic hypothermia has been shown to provide neuroprotection in mature infants exposed to perinatal asphyxia. We hypothesized that therapeutic hypothermia during ECMO would reduce the proportion of infants with brain injury, and thus later impairment.
Original languageEnglish
Pages (from-to)e1247-56
Number of pages10
Issue number5
Publication statusPublished - Nov 2013


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