Neonatal ECMO study of temperature (NEST): a randomized controlled trial

David Field; Ed Juszczak; Louise Linsell; Denis Azzopardi; Frances Cowan; Neil Marlow; David Edwards; NEST Study Collaborative Group; Marianne Thoresen

doi:10.1542/peds.2013-1754

Neonatal ECMO study of temperature (NEST): a randomized controlled trial

David Field
, Ed Juszczak
, Louise Linsell
, Denis Azzopardi
, Frances Cowan
, Neil Marlow
, David Edwards
, NEST Study Collaborative Group
, Marianne Thoresen

Research output: Contribution to journal › Article (Academic Journal) › peer-review

48 Citations (Scopus)

Abstract

Despite evidence to support the use of extracorporeal membrane oxygenation (ECMO) in defined groups of newborn infants, rates of impairment among survivors remain high. Therapeutic hypothermia has been shown to provide neuroprotection in mature infants exposed to perinatal asphyxia. We hypothesized that therapeutic hypothermia during ECMO would reduce the proportion of infants with brain injury, and thus later impairment.

Original language	English
Pages (from-to)	e1247-56
Number of pages	10
Journal	Pediatrics
Volume	132
Issue number	5
DOIs	https://doi.org/10.1542/peds.2013-1754
Publication status	Published - Nov 2013

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title = "Neonatal ECMO study of temperature (NEST): a randomized controlled trial",

abstract = "Despite evidence to support the use of extracorporeal membrane oxygenation (ECMO) in defined groups of newborn infants, rates of impairment among survivors remain high. Therapeutic hypothermia has been shown to provide neuroprotection in mature infants exposed to perinatal asphyxia. We hypothesized that therapeutic hypothermia during ECMO would reduce the proportion of infants with brain injury, and thus later impairment.",

author = "David Field and Ed Juszczak and Louise Linsell and Denis Azzopardi and Frances Cowan and Neil Marlow and David Edwards and \{NEST Study Collaborative Group\} and Marianne Thoresen",

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T1 - Neonatal ECMO study of temperature (NEST)

T2 - a randomized controlled trial

AU - Field, David

AU - Juszczak, Ed

AU - Linsell, Louise

AU - Azzopardi, Denis

AU - Cowan, Frances

AU - Marlow, Neil

AU - Edwards, David

AU - NEST Study Collaborative Group

AU - Thoresen, Marianne

PY - 2013/11

Y1 - 2013/11

N2 - Despite evidence to support the use of extracorporeal membrane oxygenation (ECMO) in defined groups of newborn infants, rates of impairment among survivors remain high. Therapeutic hypothermia has been shown to provide neuroprotection in mature infants exposed to perinatal asphyxia. We hypothesized that therapeutic hypothermia during ECMO would reduce the proportion of infants with brain injury, and thus later impairment.

AB - Despite evidence to support the use of extracorporeal membrane oxygenation (ECMO) in defined groups of newborn infants, rates of impairment among survivors remain high. Therapeutic hypothermia has been shown to provide neuroprotection in mature infants exposed to perinatal asphyxia. We hypothesized that therapeutic hypothermia during ECMO would reduce the proportion of infants with brain injury, and thus later impairment.

U2 - 10.1542/peds.2013-1754

DO - 10.1542/peds.2013-1754

M3 - Article (Academic Journal)

C2 - 24144703

SN - 0031-4005

VL - 132

SP - e1247-56

JO - Pediatrics

JF - Pediatrics

IS - 5

ER -

Neonatal ECMO study of temperature (NEST): a randomized controlled trial

Abstract

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