Next-generation genomics of Pseudomonas syringae

Heath E. O'Brien; Darrell Desveaux; David S. Guttman

doi:10.1016/j.mib.2010.12.007

Next-generation genomics of Pseudomonas syringae

Heath E. O'Brien, Darrell Desveaux, David S. Guttman^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article (Academic Journal) › peer-review

30 Citations (Scopus)

Abstract

The first wave of Pseudomonas syringae next-generation genomic studies has revealed insights into host-specific virulence and immunity, genome dynamics and evolution, and genetic and metabolic specialization. These studies have further enhanced our understanding of type III effector diversity, identified an atypical type III secretion system (T3SS) in a new clade of nonpathogenic P. syringae, identified metabolic pathways common to pathogens of woody hosts and revealed extensive genomic diversity among strains that infect common hosts. In general, these discoveries have illustrated the utility of draft genome sequencing for quickly and economically identifying candidate loci for more refined genetic and functional analyses.

Original language	English
Pages (from-to)	24-30
Number of pages	7
Journal	Current Opinion in Microbiology
Volume	14
Issue number	1
DOIs	https://doi.org/10.1016/j.mib.2010.12.007
Publication status	Published - Feb 2011

Keywords

PV. TOMATO DC3000
PLANT PATHOGEN
SEQUENCE
VIRULENCE
GENES
EVOLUTION
EFFECTOR
REVEALS
ARABIDOPSIS
LIKELIHOOD

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title = "Next-generation genomics of Pseudomonas syringae",

abstract = "The first wave of Pseudomonas syringae next-generation genomic studies has revealed insights into host-specific virulence and immunity, genome dynamics and evolution, and genetic and metabolic specialization. These studies have further enhanced our understanding of type III effector diversity, identified an atypical type III secretion system (T3SS) in a new clade of nonpathogenic P. syringae, identified metabolic pathways common to pathogens of woody hosts and revealed extensive genomic diversity among strains that infect common hosts. In general, these discoveries have illustrated the utility of draft genome sequencing for quickly and economically identifying candidate loci for more refined genetic and functional analyses.",

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author = "O'Brien, {Heath E.} and Darrell Desveaux and Guttman, {David S.}",

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AU - O'Brien, Heath E.

AU - Desveaux, Darrell

AU - Guttman, David S.

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N2 - The first wave of Pseudomonas syringae next-generation genomic studies has revealed insights into host-specific virulence and immunity, genome dynamics and evolution, and genetic and metabolic specialization. These studies have further enhanced our understanding of type III effector diversity, identified an atypical type III secretion system (T3SS) in a new clade of nonpathogenic P. syringae, identified metabolic pathways common to pathogens of woody hosts and revealed extensive genomic diversity among strains that infect common hosts. In general, these discoveries have illustrated the utility of draft genome sequencing for quickly and economically identifying candidate loci for more refined genetic and functional analyses.

AB - The first wave of Pseudomonas syringae next-generation genomic studies has revealed insights into host-specific virulence and immunity, genome dynamics and evolution, and genetic and metabolic specialization. These studies have further enhanced our understanding of type III effector diversity, identified an atypical type III secretion system (T3SS) in a new clade of nonpathogenic P. syringae, identified metabolic pathways common to pathogens of woody hosts and revealed extensive genomic diversity among strains that infect common hosts. In general, these discoveries have illustrated the utility of draft genome sequencing for quickly and economically identifying candidate loci for more refined genetic and functional analyses.

KW - PV. TOMATO DC3000

KW - PLANT PATHOGEN

KW - SEQUENCE

KW - VIRULENCE

KW - GENES

KW - EVOLUTION

KW - EFFECTOR

KW - REVEALS

KW - ARABIDOPSIS

KW - LIKELIHOOD

U2 - 10.1016/j.mib.2010.12.007

DO - 10.1016/j.mib.2010.12.007

M3 - Review article (Academic Journal)

C2 - 21233007

SN - 1369-5274

VL - 14

SP - 24

EP - 30

JO - Current Opinion in Microbiology

JF - Current Opinion in Microbiology

IS - 1

ER -

Next-generation genomics of Pseudomonas syringae

Abstract

Keywords

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