Ninety-day mortality after elective total hip replacement: 1549 patients using aspirin as a thromboprophylactic agent

MC Parry, V Wylde, AW Blom

Research output: Contribution to journalArticle (Academic Journal)peer-review

44 Citations (Scopus)

Abstract

Thromboprophylaxis after elective orthopaedic surgery remains controversial. Recent guidelines from the National Institute for Clinical Excellence (NICE) have suggested that low molecular weight heparin should be given to all patients undergoing total hip replacement. The British Orthopaedic Association is currently debating this guideline with NICE, as it is not clear whether published evidence supports this view. We present the early mortality in our unit after total hip replacement using aspirin as chemical thromboprophylaxis. The 30-day and 90-day mortality after primary total hip arthroplasty was zero. We compare this with that reported previously from our unit without using chemical thromboprophylaxis. With the introduction of routine aspirin thromboprophylaxis, deaths from cardiovascular causes have dropped from 0.75% to zero. These results demonstrate that there is a strong argument for the routine administration of aspirin after elective total hip replacement.
Translated title of the contributionNinety-day mortality after elective total hip replacement: 1549 patients using aspirin as a thromboprophylactic agent
Original languageEnglish
Pages (from-to)306 - 307
Number of pages2
JournalJournal of Bone and Joint Surgery
Volume90(3)
DOIs
Publication statusPublished - Mar 2008

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