Abstract
Objective:
To develop an aesthetic resin composite using a nitrogen-doped titanium dioxide (N-TiO2) filler that possesses antibacterial properties against Streptococcus mutans.
Methods:
N-TiO2 powder was manufactured by calcining commercial TiO2 with urea. Free radical release from the N-TiO2 powder under visible light irradiation was analysed using UV-Vis spectrophotometry. The N-TiO2 powder was incorporated into a dental resin and the photocatalytic activity assessed using a dye under both visible light and dark conditions. The metabolic activity of Streptococcus mutans grown on the N-TiO2/resin composite discs was quantified by XTT reduction assay to assess the antibacterial properties of the resin.
Results:
Doping nitrogen of TiO2 resulted in a band gap shift towards the visible light spectrum, which enabled the powder to release reactive oxygen species when exposed to visible light. When incorporated into a dental resin, the N-TiO2/resin composite still demonstrated sustained release of reactive oxygen species, maintaining its photocatalytic activity and showing an antibacterial effect towards Streptococcus mutans under visible light compared to dark conditions (P<0.05).
Significance:
N-TiO2 filled resin composite shows great promise as a potential aesthetic resin-based adhesive for orthodontic bonding.
To develop an aesthetic resin composite using a nitrogen-doped titanium dioxide (N-TiO2) filler that possesses antibacterial properties against Streptococcus mutans.
Methods:
N-TiO2 powder was manufactured by calcining commercial TiO2 with urea. Free radical release from the N-TiO2 powder under visible light irradiation was analysed using UV-Vis spectrophotometry. The N-TiO2 powder was incorporated into a dental resin and the photocatalytic activity assessed using a dye under both visible light and dark conditions. The metabolic activity of Streptococcus mutans grown on the N-TiO2/resin composite discs was quantified by XTT reduction assay to assess the antibacterial properties of the resin.
Results:
Doping nitrogen of TiO2 resulted in a band gap shift towards the visible light spectrum, which enabled the powder to release reactive oxygen species when exposed to visible light. When incorporated into a dental resin, the N-TiO2/resin composite still demonstrated sustained release of reactive oxygen species, maintaining its photocatalytic activity and showing an antibacterial effect towards Streptococcus mutans under visible light compared to dark conditions (P<0.05).
Significance:
N-TiO2 filled resin composite shows great promise as a potential aesthetic resin-based adhesive for orthodontic bonding.
Original language | English |
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Pages (from-to) | 147-157 |
Number of pages | 11 |
Journal | Dental Materials |
Volume | 38 |
Issue number | 1 |
Early online date | 24 Nov 2021 |
DOIs | |
Publication status | Published - 19 Jan 2022 |
Bibliographical note
Publisher Copyright:© 2021 The Academy of Dental Materials
Keywords
- Nitrogen doped titanium dioxide
- Antibacterial
- Dental adhesive
- Orthodontics