Edward Balmond, Eoghan McGarrigle, Carmen Galan

Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary


(used as hydrogen-bonding organocatalyst in a wide variety of reactions)

Alternate Name: Schreiner's thiourea.

Physical Data: mp 172–173 °C,1 pKa (DMSO) 8.4/8.5.2, 3

Solubility: soluble in methanol, ethanol, Et2O, CH2Cl2, EtOAc, MeCN, DMSO, and toluene; insoluble in H2O and hexane.

Form Supplied in: commercially available as a white solid.

Purification: recrystallization from CHCl3 then either hexane/Et2O1 or hexane/EtOAc.4

Handling, Storage, and Precautions: bench stable; keep container tightly closed and store in a cool and dark place, away from incompatible materials such as oxidizing agents.

Original languageEnglish
Title of host publicatione-EROS Encyclopedia of Reagents for Organic Synthesis
Number of pages4
ISBN (Print)9780470842898
Publication statusPublished - 27 May 2014


Dive into the research topics of 'N,N′-Bis[3,5-bis(trifluoromethyl)phenyl]thiourea'. Together they form a unique fingerprint.

Cite this