Abstract
Recent reports have suggested that variability in the alpha2-macroglobulin gene is a genetic risk factor for Alzheimer's disease. Here we have both tested a common polymorphism in the gene (I1000V) for association with the disease in a four-site case control study design, and tested the locus for linkage in a large series of sibpairs afflicted with late onset disease. Our results fail to show an association between this polymorphism and disease.
Translated title of the contribution | No association between the alpha-2 macroglobulin 11000V polymorphism and Alzheimer's disease |
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Original language | English |
Pages (from-to) | 139 - 139 |
Number of pages | 1 |
Journal | Neuroscience Letters |
Volume | 262 |
DOIs | |
Publication status | Published - Mar 1999 |
Bibliographical note
Publisher: ElsevierResearch Groups and Themes
- Cerebrovascular and Dementia Research Group