Nocturia is an orphan symptom seeking caring specialties willing to adopt

Marcus J Drake; Jonathan  Rees; Emily J Henderson

doi:10.1016/j.euf.2022.01.006

Nocturia is an orphan symptom seeking caring specialties willing to adopt

Marcus J Drake^*, Jonathan Rees, Emily J Henderson

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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Abstract

In functional urology, “If getting nowhere with treatment, review the diagnosis” is an important aphorism. The most recent edition of Abrams’ Urodynamics describes a man with bothersome nocturia who received 11 different drugs over a 5-yr period [ [1] ]. All were “urological” drugs (except for two rounds of furosemide) yet none had worked, so the patient was referred for urodynamics with a view to prostate surgery. When he presented for the test, he was soon identified as having a low chance of benefiting, as indicated by the recent UPSTREAM results [ [2] ]. New enquiry revealed that he intermittently stopped breathing at night, which fundamentally altered the trajectory of his management. Identification of obstructive sleep apnoea (OSA), and requisite treatment, led to almost full resolution of the troubling nocturia.

Original language	English
Pages (from-to)	1-3
Number of pages	3
Journal	European Urology Focus
Volume	8
Issue number	1
Early online date	21 Jan 2022
DOIs	https://doi.org/10.1016/j.euf.2022.01.006
Publication status	E-pub ahead of print - 21 Jan 2022

Bibliographical note

Funding Information:
Conflicts of interest : All of the authors are grant holders for the PLANET study funded by the National Institute for Health Research (NIHR) under its Research for Patient Benefit programme (grant NIHR RfPB PB-PG-1217-20034). The views expressed are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care. Marcus J. Drake is a paid advisory board member for Ferring, a paid speaker for Astellas and Pfizer, and an unpaid advisory board member for the ICIQ research project.

Research Groups and Themes

Ageing and Movement Research Group

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This is the accepted author manuscript (AAM). The final published version (version of record) is available online via Elsevier at https://doi.org/10.1016/j.euf.2022.01.006. Please refer to any applicable terms of use of the publisher.
Accepted author manuscript, 260 KBLicence: CC BY-NC-ND
Supplementary information 1 PDF
This is the accepted author manuscript (AAM). The final published version (version of record) is available online via Elsevier at https://doi.org/10.1016/j.euf.2022.01.006. Please refer to any applicable terms of use of the publisher.
Accepted author manuscript, 462 KBLicence: CC BY-NC-ND
Supplementary information 2 PDF
This is the accepted author manuscript (AAM). The final published version (version of record) is available online via Elsevier at https://doi.org/10.1016/j.euf.2022.01.006. Please refer to any applicable terms of use of the publisher.
Accepted author manuscript, 1.45 MBLicence: CC BY-NC-ND

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@article{676576a1d8f842248c0078c66a144f84,

title = "Nocturia is an orphan symptom seeking caring specialties willing to adopt",

abstract = "In functional urology, “If getting nowhere with treatment, review the diagnosis” is an important aphorism. The most recent edition of Abrams{\textquoteright} Urodynamics describes a man with bothersome nocturia who received 11 different drugs over a 5-yr period [ [1] ]. All were “urological” drugs (except for two rounds of furosemide) yet none had worked, so the patient was referred for urodynamics with a view to prostate surgery. When he presented for the test, he was soon identified as having a low chance of benefiting, as indicated by the recent UPSTREAM results [ [2] ]. New enquiry revealed that he intermittently stopped breathing at night, which fundamentally altered the trajectory of his management. Identification of obstructive sleep apnoea (OSA), and requisite treatment, led to almost full resolution of the troubling nocturia.",

author = "Drake, {Marcus J} and Jonathan Rees and Henderson, {Emily J}",

note = "Funding Information: Conflicts of interest : All of the authors are grant holders for the PLANET study funded by the National Institute for Health Research (NIHR) under its Research for Patient Benefit programme (grant NIHR RfPB PB-PG-1217-20034). The views expressed are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care. Marcus J. Drake is a paid advisory board member for Ferring, a paid speaker for Astellas and Pfizer, and an unpaid advisory board member for the ICIQ research project.",

year = "2022",

month = jan,

day = "21",

doi = "10.1016/j.euf.2022.01.006",

language = "English",

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pages = "1--3",

journal = "European Urology Focus",

issn = "2405-4569",

publisher = "Elsevier B.V.",

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T1 - Nocturia is an orphan symptom seeking caring specialties willing to adopt

AU - Drake, Marcus J

AU - Rees, Jonathan

AU - Henderson, Emily J

N1 - Funding Information: Conflicts of interest : All of the authors are grant holders for the PLANET study funded by the National Institute for Health Research (NIHR) under its Research for Patient Benefit programme (grant NIHR RfPB PB-PG-1217-20034). The views expressed are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care. Marcus J. Drake is a paid advisory board member for Ferring, a paid speaker for Astellas and Pfizer, and an unpaid advisory board member for the ICIQ research project.

PY - 2022/1/21

Y1 - 2022/1/21

N2 - In functional urology, “If getting nowhere with treatment, review the diagnosis” is an important aphorism. The most recent edition of Abrams’ Urodynamics describes a man with bothersome nocturia who received 11 different drugs over a 5-yr period [ [1] ]. All were “urological” drugs (except for two rounds of furosemide) yet none had worked, so the patient was referred for urodynamics with a view to prostate surgery. When he presented for the test, he was soon identified as having a low chance of benefiting, as indicated by the recent UPSTREAM results [ [2] ]. New enquiry revealed that he intermittently stopped breathing at night, which fundamentally altered the trajectory of his management. Identification of obstructive sleep apnoea (OSA), and requisite treatment, led to almost full resolution of the troubling nocturia.

AB - In functional urology, “If getting nowhere with treatment, review the diagnosis” is an important aphorism. The most recent edition of Abrams’ Urodynamics describes a man with bothersome nocturia who received 11 different drugs over a 5-yr period [ [1] ]. All were “urological” drugs (except for two rounds of furosemide) yet none had worked, so the patient was referred for urodynamics with a view to prostate surgery. When he presented for the test, he was soon identified as having a low chance of benefiting, as indicated by the recent UPSTREAM results [ [2] ]. New enquiry revealed that he intermittently stopped breathing at night, which fundamentally altered the trajectory of his management. Identification of obstructive sleep apnoea (OSA), and requisite treatment, led to almost full resolution of the troubling nocturia.

U2 - 10.1016/j.euf.2022.01.006

DO - 10.1016/j.euf.2022.01.006

M3 - Article (Academic Journal)

C2 - 35074277

SN - 2405-4569

VL - 8

SP - 1

EP - 3

JO - European Urology Focus

JF - European Urology Focus

IS - 1

ER -

Nocturia is an orphan symptom seeking caring specialties willing to adopt

Abstract

Bibliographical note

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