Projects per year
Precise surface nanopatterning is a promising route for predictable control of cellular behavior on biomedical materials. There is currently a gap in taking such precision engineered surfaces from the laboratory to clinically relevant implant materials such as titanium (Ti). In this work, anodization of Ti surfaces was performed in combination with block copolymer templates to create highly ordered and tunable oxide nanopatterns. Secondary ion mass spectroscopy (SIMS) and X-ray photoelectron spectroscopy (XPS) analyses showed that the composition of the anodized structures was mainly titania with small amounts of nitrogen left from the block copolymer. It was further demonstrated that these nanopatterns can be superimposed on more complex shaped Ti surfaces such as microbeads, using the same technique. Human mesenchymal stem cells were cultured on Ti microbead surfaces, with and without nanopatterns, in vitro to study the effect of nanotopography on Ti surfaces. The results presented in this work demonstrate a promising method of producing highly defined and well-arranged surface nanopatterns on Ti implant surfaces.
- RAY PHOTOELECTRON-SPECTROSCOPY
- block copolymers
- stem cells
- TIO2 THIN-FILMS
- ORDERED ARRAYS
- DIBLOCK COPOLYMER
FingerprintDive into the research topics of 'Novel Anodization Technique Using a Block Copolymer Template for Nanopatterning of Titanium Implant Surfaces'. Together they form a unique fingerprint.
- 2 Finished
MICRO- AND NANO-PATTERNING OF TITANIUM SURFACES FOR OPTIMAL OSSEOINTERGRATION OF ORTHOPAEDIC IMPLANTS
1/06/09 → 1/06/12
CREATING 3D BIOMIMETIC COLLAGEN EXTRA-CELLULAR MATRICES FOR CELL BIOLOGY AND TISSUE ENGINEERING APPLICATIONS
26/11/08 → 26/03/10