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Observation of pyridine aggregation in aqueous solution using neutron scattering experiments and MD simulations

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Observation of pyridine aggregation in aqueous solution using neutron scattering experiments and MD simulations. / Mason, PE; Neilson, GW; Dempsey, CE; Price, DL; Saboungi, M-L; Brady, JW.

In: Journal of Physical Chemistry B, Vol. 114 (16), 04.2010, p. 5412 - 5419.

Research output: Contribution to journalArticle

Harvard

Mason, PE, Neilson, GW, Dempsey, CE, Price, DL, Saboungi, M-L & Brady, JW 2010, 'Observation of pyridine aggregation in aqueous solution using neutron scattering experiments and MD simulations', Journal of Physical Chemistry B, vol. 114 (16), pp. 5412 - 5419. https://doi.org/10.1021/jp9097827

APA

Mason, PE., Neilson, GW., Dempsey, CE., Price, DL., Saboungi, M-L., & Brady, JW. (2010). Observation of pyridine aggregation in aqueous solution using neutron scattering experiments and MD simulations. Journal of Physical Chemistry B, 114 (16), 5412 - 5419. https://doi.org/10.1021/jp9097827

Vancouver

Mason PE, Neilson GW, Dempsey CE, Price DL, Saboungi M-L, Brady JW. Observation of pyridine aggregation in aqueous solution using neutron scattering experiments and MD simulations. Journal of Physical Chemistry B. 2010 Apr;114 (16):5412 - 5419. https://doi.org/10.1021/jp9097827

Author

Mason, PE ; Neilson, GW ; Dempsey, CE ; Price, DL ; Saboungi, M-L ; Brady, JW. / Observation of pyridine aggregation in aqueous solution using neutron scattering experiments and MD simulations. In: Journal of Physical Chemistry B. 2010 ; Vol. 114 (16). pp. 5412 - 5419.

Bibtex

@article{d46e509433ad43789ec1c70bd1b72c9a,
title = "Observation of pyridine aggregation in aqueous solution using neutron scattering experiments and MD simulations",
abstract = "Neutron diffraction with isotopic substitution (NDIS) experiments have been used to examine the structuring of aqueous solutions of pyridine. A new method is described for extracting the structure factors relating to intermolecular correlations from neutron scattering experiments on liquid solutions of complex molecular species. This approach performs experiments at different concentrations and exploits the intramolecular coordination number concentration invariance (ICNCI) to separate the internal and intermolecular contributions to the total intensities. The ability of this method to deconvolute molecular and intermolecular correlations is tested and demonstrated using simulated neutron scattering results predicted from molecular dynamics simulations of aqueous solutions of the polyatomic solute pyridine in which the inter- and intramolecular terms are known. The method is then implemented using neutron scattering measurements on solutions of pyridine. The results confirm that pyridine shows a significant propensity to aggregate in solution and demonstrate the prospects for the future application of the ICNCI approach to the study of large polyatomic solutes using next-generation neutron sources and detectors.",
author = "PE Mason and GW Neilson and CE Dempsey and DL Price and M-L Saboungi and JW Brady",
year = "2010",
month = "4",
doi = "10.1021/jp9097827",
language = "English",
volume = "114 (16)",
pages = "5412 -- 5419",
journal = "Journal of Physical Chemistry B",
issn = "1520-6106",
publisher = "American Chemical Society",

}

RIS - suitable for import to EndNote

TY - JOUR

T1 - Observation of pyridine aggregation in aqueous solution using neutron scattering experiments and MD simulations

AU - Mason, PE

AU - Neilson, GW

AU - Dempsey, CE

AU - Price, DL

AU - Saboungi, M-L

AU - Brady, JW

PY - 2010/4

Y1 - 2010/4

N2 - Neutron diffraction with isotopic substitution (NDIS) experiments have been used to examine the structuring of aqueous solutions of pyridine. A new method is described for extracting the structure factors relating to intermolecular correlations from neutron scattering experiments on liquid solutions of complex molecular species. This approach performs experiments at different concentrations and exploits the intramolecular coordination number concentration invariance (ICNCI) to separate the internal and intermolecular contributions to the total intensities. The ability of this method to deconvolute molecular and intermolecular correlations is tested and demonstrated using simulated neutron scattering results predicted from molecular dynamics simulations of aqueous solutions of the polyatomic solute pyridine in which the inter- and intramolecular terms are known. The method is then implemented using neutron scattering measurements on solutions of pyridine. The results confirm that pyridine shows a significant propensity to aggregate in solution and demonstrate the prospects for the future application of the ICNCI approach to the study of large polyatomic solutes using next-generation neutron sources and detectors.

AB - Neutron diffraction with isotopic substitution (NDIS) experiments have been used to examine the structuring of aqueous solutions of pyridine. A new method is described for extracting the structure factors relating to intermolecular correlations from neutron scattering experiments on liquid solutions of complex molecular species. This approach performs experiments at different concentrations and exploits the intramolecular coordination number concentration invariance (ICNCI) to separate the internal and intermolecular contributions to the total intensities. The ability of this method to deconvolute molecular and intermolecular correlations is tested and demonstrated using simulated neutron scattering results predicted from molecular dynamics simulations of aqueous solutions of the polyatomic solute pyridine in which the inter- and intramolecular terms are known. The method is then implemented using neutron scattering measurements on solutions of pyridine. The results confirm that pyridine shows a significant propensity to aggregate in solution and demonstrate the prospects for the future application of the ICNCI approach to the study of large polyatomic solutes using next-generation neutron sources and detectors.

U2 - 10.1021/jp9097827

DO - 10.1021/jp9097827

M3 - Article

C2 - 20369858

VL - 114 (16)

SP - 5412

EP - 5419

JO - Journal of Physical Chemistry B

JF - Journal of Physical Chemistry B

SN - 1520-6106

ER -