Observational study on variability between biobanks in the estimation of DNA concentration

Jay Brown; Alexander N Donev; Charalampos Aslanidis; Pippa Bracegirdle; Katherine P Dixon; Manuela Foedinger; Rhian Gwilliam; Matthew Hardy; Thomas Illig; Xiayi Ke; Dagni Krinka; Camilla Lagerberg; Päivi Laiho; David H Lewis; Wendy McArdle; Simon Patton; Susan M Ring; Gerd Schmitz; Helen Stevens; Gunnel Tybring; H Erich Wichmann; William E R Ollier; Martin A Yuille

doi:10.1186/1756-0500-2-208

Observational study on variability between biobanks in the estimation of DNA concentration

Jay Brown, Alexander N Donev, Charalampos Aslanidis, Pippa Bracegirdle, Katherine P Dixon, Manuela Foedinger, Rhian Gwilliam, Matthew Hardy, Thomas Illig, Xiayi Ke, Dagni Krinka, Camilla Lagerberg, Päivi Laiho, David H Lewis, Wendy McArdle, Simon Patton, Susan M Ring, Gerd Schmitz, Helen Stevens, Gunnel TybringH Erich Wichmann, William E R Ollier, Martin A Yuille

Bristol Medical School (PHS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

7 Citations (Scopus)

Abstract

There is little confidence in the consistency of estimation of DNA concentrations when samples move between laboratories. Evidence on this consistency is largely anecdotal. Therefore there is a need first to measure this consistency among different laboratories and then identify and implement remedies. A pilot experiment to test logistics and provide initial data on consistency was therefore conceived.

Original language	English
Pages (from-to)	208
Journal	BMC Research Notes
Volume	2
DOIs	https://doi.org/10.1186/1756-0500-2-208
Publication status	Published - 2009

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Brown, J., Donev, A. N., Aslanidis, C., Bracegirdle, P., Dixon, K. P., Foedinger, M., Gwilliam, R., Hardy, M., Illig, T., Ke, X., Krinka, D., Lagerberg, C., Laiho, P., Lewis, D. H., McArdle, W., Patton, S., Ring, S. M., Schmitz, G., Stevens, H., ... Yuille, M. A. (2009). Observational study on variability between biobanks in the estimation of DNA concentration. BMC Research Notes, 2, 208. https://doi.org/10.1186/1756-0500-2-208

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title = "Observational study on variability between biobanks in the estimation of DNA concentration",

abstract = "There is little confidence in the consistency of estimation of DNA concentrations when samples move between laboratories. Evidence on this consistency is largely anecdotal. Therefore there is a need first to measure this consistency among different laboratories and then identify and implement remedies. A pilot experiment to test logistics and provide initial data on consistency was therefore conceived.",

author = "Jay Brown and Donev, {Alexander N} and Charalampos Aslanidis and Pippa Bracegirdle and Dixon, {Katherine P} and Manuela Foedinger and Rhian Gwilliam and Matthew Hardy and Thomas Illig and Xiayi Ke and Dagni Krinka and Camilla Lagerberg and P{\"a}ivi Laiho and Lewis, {David H} and Wendy McArdle and Simon Patton and Ring, {Susan M} and Gerd Schmitz and Helen Stevens and Gunnel Tybring and Wichmann, {H Erich} and Ollier, {William E R} and Yuille, {Martin A}",

year = "2009",

doi = "10.1186/1756-0500-2-208",

language = "English",

volume = "2",

pages = "208",

journal = "BMC Research Notes",

issn = "1756-0500",

publisher = "BioMed Central",

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Brown, J, Donev, AN, Aslanidis, C, Bracegirdle, P, Dixon, KP, Foedinger, M, Gwilliam, R, Hardy, M, Illig, T, Ke, X, Krinka, D, Lagerberg, C, Laiho, P, Lewis, DH, McArdle, W, Patton, S, Ring, SM, Schmitz, G, Stevens, H, Tybring, G, Wichmann, HE, Ollier, WER & Yuille, MA 2009, 'Observational study on variability between biobanks in the estimation of DNA concentration', BMC Research Notes, vol. 2, pp. 208. https://doi.org/10.1186/1756-0500-2-208

TY - JOUR

T1 - Observational study on variability between biobanks in the estimation of DNA concentration

AU - Brown, Jay

AU - Donev, Alexander N

AU - Aslanidis, Charalampos

AU - Bracegirdle, Pippa

AU - Dixon, Katherine P

AU - Foedinger, Manuela

AU - Gwilliam, Rhian

AU - Hardy, Matthew

AU - Illig, Thomas

AU - Ke, Xiayi

AU - Krinka, Dagni

AU - Lagerberg, Camilla

AU - Laiho, Päivi

AU - Lewis, David H

AU - McArdle, Wendy

AU - Patton, Simon

AU - Ring, Susan M

AU - Schmitz, Gerd

AU - Stevens, Helen

AU - Tybring, Gunnel

AU - Wichmann, H Erich

AU - Ollier, William E R

AU - Yuille, Martin A

PY - 2009

Y1 - 2009

N2 - There is little confidence in the consistency of estimation of DNA concentrations when samples move between laboratories. Evidence on this consistency is largely anecdotal. Therefore there is a need first to measure this consistency among different laboratories and then identify and implement remedies. A pilot experiment to test logistics and provide initial data on consistency was therefore conceived.

AB - There is little confidence in the consistency of estimation of DNA concentrations when samples move between laboratories. Evidence on this consistency is largely anecdotal. Therefore there is a need first to measure this consistency among different laboratories and then identify and implement remedies. A pilot experiment to test logistics and provide initial data on consistency was therefore conceived.

U2 - 10.1186/1756-0500-2-208

DO - 10.1186/1756-0500-2-208

M3 - Article (Academic Journal)

C2 - 19825187

SN - 1756-0500

VL - 2

SP - 208

JO - BMC Research Notes

JF - BMC Research Notes

ER -

Observational study on variability between biobanks in the estimation of DNA concentration

Abstract

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