Observations of tetrel bonding between sp3-carbon and THF

Victoria L. Heywood, Thomas P. J. Alford, Julius J. Roeleveld, Siebe J. Lekanne Deprez, Abraham Verhoofstad, Jarl Ivar van der Vlugt, Sérgio R. Domingos, Melanie Schnell, Anthony P. Davis, Tiddo J. Mooibroek

Research output: Contribution to journalArticle (Academic Journal)peer-review

41 Citations (Scopus)
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Abstract

We report the direct observation of tetrel bonding interactions between sp3-carbons of the supramolecular synthon 3,3-dimethyl-tetracyanocyclopropane (1) and tetrahydrofuran in the gas and crystalline phase. The intermolecular contact is established via σ-holes and is driven mainly by electrostatic forces. The complex manifests distinct binding geometries when captured in the crystalline phase and in the gas phase. We elucidate these binding trends using complementary gas phase quantum chemical calculations and find a total binding energy of −11.2 kcal mol−1 for the adduct. Our observations pave the way for novel strategies to engineer sp3-C centred non-covalent bonding schemes for supramolecular chemistry.
Original languageEnglish
Pages (from-to)5289-5293
JournalChemical Science
Volume11
DOIs
Publication statusPublished - 7 May 2020

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