Olefin cross-metathesis for the synthesis of heteroaromatic compounds

Timothy J. Donohoe, John F. Bower, Louis K. M. Chan

Research output: Contribution to journalArticle (Academic Journal)peer-review

58 Citations (Scopus)

Abstract

The olefin metathesis reaction has underpinned spectacular achievements in organic synthesis in recent years. Arguably, metathesis has now become the foremost choice for a carbon-carbon double bond disconnection. Despite this general utility, de novo routes to heteroaromatic compounds using the cross-metathesis (CM) reaction have only recently emerged as an efficient strategy. This approach allows a convergent union of simple, functionalised, three- to four-carbon olefinic core building blocks, to generate furans, pyrroles and pyridines with a high degree of control of substitution pattern in the product.

Original languageEnglish
Pages (from-to)1322-1328
Number of pages7
JournalOrganic and Biomolecular Chemistry
Volume10
Issue number7
DOIs
Publication statusPublished - 2012

Fingerprint

Dive into the research topics of 'Olefin cross-metathesis for the synthesis of heteroaromatic compounds'. Together they form a unique fingerprint.

Cite this