Open questions: what about the 'other' Rho GTPases?

Anne J Ridley

doi:10.1186/s12915-016-0289-7

Open questions: what about the 'other' Rho GTPases?

Anne J Ridley

Research output: Contribution to journal › Comment/debate (Academic Journal) › peer-review

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Abstract

Rho GTPases have many and diverse roles in cell physiology, and some family members are very well studied, including RhoA, Rac1 and Cdc42. But many are relatively neglected, and fundamental questions about their mechanisms and functions remain open.

Original language	English
Pages (from-to)	64
Journal	BMC Biology
Volume	14
DOIs	https://doi.org/10.1186/s12915-016-0289-7
Publication status	Published - 4 Aug 2016

Keywords

Gene Expression Regulation
Humans
Signal Transduction
cdc42 GTP-Binding Protein
rac1 GTP-Binding Protein
rho GTP-Binding Proteins
rhoA GTP-Binding Protein
Editorial

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This is the final published version of the article (version of record). It first appeared online via Biomed Central at https://doi.org/10.1186/s12915-016-0289-7 . Please refer to any applicable terms of use of the publisher.
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title = "Open questions: what about the 'other' Rho GTPases?",

abstract = "Rho GTPases have many and diverse roles in cell physiology, and some family members are very well studied, including RhoA, Rac1 and Cdc42. But many are relatively neglected, and fundamental questions about their mechanisms and functions remain open.",

keywords = "Gene Expression Regulation, Humans, Signal Transduction, cdc42 GTP-Binding Protein, rac1 GTP-Binding Protein, rho GTP-Binding Proteins, rhoA GTP-Binding Protein, Editorial",

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AB - Rho GTPases have many and diverse roles in cell physiology, and some family members are very well studied, including RhoA, Rac1 and Cdc42. But many are relatively neglected, and fundamental questions about their mechanisms and functions remain open.

KW - Gene Expression Regulation

KW - Humans

KW - Signal Transduction

KW - cdc42 GTP-Binding Protein

KW - rac1 GTP-Binding Protein

KW - rho GTP-Binding Proteins

KW - rhoA GTP-Binding Protein

KW - Editorial

U2 - 10.1186/s12915-016-0289-7

DO - 10.1186/s12915-016-0289-7

M3 - Comment/debate (Academic Journal)

C2 - 27491358

SN - 1741-7007

VL - 14

SP - 64

JO - BMC Biology

JF - BMC Biology

ER -

Open questions: what about the 'other' Rho GTPases?

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