Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae

CL Trotter; J McVernon; ME Ramsay; CG Whitney; EK Mulholland; D Goldblatt; J Hombach; M-P Kieny; subgroup On behalf of the SAGE

doi:10.1016/j.vaccine.2008.05.073

Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae

CL Trotter
, J McVernon
, ME Ramsay
, CG Whitney
, EK Mulholland
, D Goldblatt
, J Hombach
, M-P Kieny
, subgroup On behalf of the SAGE

Bristol Medical School (PHS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

132 Citations (Scopus)

Abstract

Conjugate vaccines exist that offer protection against disease caused by Haemophilus influenzae type b (Hib), and selected serogroups/serotypes of Neisseria meningitidis and Streptococcus pneumoniae. These vaccines are not only able to prevent serious disease, but they also provide protection against asymptomatic carriage. The resulting herd immunity effects have been striking, and have played an important role in the public health success of conjugate vaccination programmes. The aim of this paper is to review the state of the current evidence on conjugate vaccines and to identify important areas for further study, in order to inform the debate regarding the best use of these vaccines

Translated title of the contribution	Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae
Original language	English
Pages (from-to)	4434 - 4445
Journal	Vaccine
Volume	26
DOIs	https://doi.org/10.1016/j.vaccine.2008.05.073
Publication status	Published - 2008

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SDG 3 Good Health and Well-being

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Trotter, CL., McVernon, J., Ramsay, ME., Whitney, CG., Mulholland, EK., Goldblatt, D., Hombach, J., Kieny, M.-P., & On behalf of the SAGE, S. (2008). Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae. Vaccine, 26, 4434 - 4445. https://doi.org/10.1016/j.vaccine.2008.05.073

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abstract = "Conjugate vaccines exist that offer protection against disease caused by Haemophilus influenzae type b (Hib), and selected serogroups/serotypes of Neisseria meningitidis and Streptococcus pneumoniae. These vaccines are not only able to prevent serious disease, but they also provide protection against asymptomatic carriage. The resulting herd immunity effects have been striking, and have played an important role in the public health success of conjugate vaccination programmes. The aim of this paper is to review the state of the current evidence on conjugate vaccines and to identify important areas for further study, in order to inform the debate regarding the best use of these vaccines",

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Trotter, CL, McVernon, J, Ramsay, ME, Whitney, CG, Mulholland, EK, Goldblatt, D, Hombach, J, Kieny, M-P & On behalf of the SAGE, S 2008, 'Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae', Vaccine, vol. 26, pp. 4434 - 4445. https://doi.org/10.1016/j.vaccine.2008.05.073

TY - JOUR

T1 - Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae

AU - Trotter, CL

AU - McVernon, J

AU - Ramsay, ME

AU - Whitney, CG

AU - Mulholland, EK

AU - Goldblatt, D

AU - Hombach, J

AU - Kieny, M-P

AU - On behalf of the SAGE, subgroup

PY - 2008

Y1 - 2008

N2 - Conjugate vaccines exist that offer protection against disease caused by Haemophilus influenzae type b (Hib), and selected serogroups/serotypes of Neisseria meningitidis and Streptococcus pneumoniae. These vaccines are not only able to prevent serious disease, but they also provide protection against asymptomatic carriage. The resulting herd immunity effects have been striking, and have played an important role in the public health success of conjugate vaccination programmes. The aim of this paper is to review the state of the current evidence on conjugate vaccines and to identify important areas for further study, in order to inform the debate regarding the best use of these vaccines

AB - Conjugate vaccines exist that offer protection against disease caused by Haemophilus influenzae type b (Hib), and selected serogroups/serotypes of Neisseria meningitidis and Streptococcus pneumoniae. These vaccines are not only able to prevent serious disease, but they also provide protection against asymptomatic carriage. The resulting herd immunity effects have been striking, and have played an important role in the public health success of conjugate vaccination programmes. The aim of this paper is to review the state of the current evidence on conjugate vaccines and to identify important areas for further study, in order to inform the debate regarding the best use of these vaccines

U2 - 10.1016/j.vaccine.2008.05.073

DO - 10.1016/j.vaccine.2008.05.073

M3 - Article (Academic Journal)

C2 - 18617296

SN - 1873-2518

VL - 26

SP - 4434

EP - 4445

JO - Vaccine

JF - Vaccine

ER -

Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae

Abstract

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