Oral hairy leukoplakia arising in a patient with hairy cell leukaemia: the first reported case

Gemma Davis; Alexandra Perks; Pemith Liyanage; Konrad Staines

doi:10.1136/bcr-2016-218663

Oral hairy leukoplakia arising in a patient with hairy cell leukaemia: the first reported case

Gemma Davis, Alexandra Perks, Pemith Liyanage, Konrad Staines

Bristol Dental School

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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Abstract

Oral hairy leukoplakia (OHL) is an oral mucosal lesion that is associated with Epstein-Barr virus infection. It commonly presents as an asymptomatic, non-removable white patch on the lateral borders of the tongue in individuals who are immunocompromised. Historically, OHL was thought to be pathognomonic of HIV infection; however, it is now an established phenomenon in a range of conditions affecting immune competence. Hairy cell leukaemia (HCL) is a rare chronic B cell lymphoproliferative disease named after the distinctive cytology of the atypical cells. We report the first case of OHL arising in an individual with HCL that resolved following remission of the haematological malignancy.

Original language	English
Journal	BMJ Case Reports
Volume	2017
DOIs	https://doi.org/10.1136/bcr-2016-218663
Publication status	Published - 6 Apr 2017

Bibliographical note

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Epstein-Barr Virus Infections/complications
Humans
Leukemia, Hairy Cell/drug therapy
Leukoplakia, Hairy/diagnosis
Lichen Planus, Oral/diagnosis
Male
Middle Aged
Purines

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title = "Oral hairy leukoplakia arising in a patient with hairy cell leukaemia: the first reported case",

abstract = "Oral hairy leukoplakia (OHL) is an oral mucosal lesion that is associated with Epstein-Barr virus infection. It commonly presents as an asymptomatic, non-removable white patch on the lateral borders of the tongue in individuals who are immunocompromised. Historically, OHL was thought to be pathognomonic of HIV infection; however, it is now an established phenomenon in a range of conditions affecting immune competence. Hairy cell leukaemia (HCL) is a rare chronic B cell lymphoproliferative disease named after the distinctive cytology of the atypical cells. We report the first case of OHL arising in an individual with HCL that resolved following remission of the haematological malignancy.",

keywords = "Epstein-Barr Virus Infections/complications, Humans, Leukemia, Hairy Cell/drug therapy, Leukoplakia, Hairy/diagnosis, Lichen Planus, Oral/diagnosis, Male, Middle Aged, Purines",

author = "Gemma Davis and Alexandra Perks and Pemith Liyanage and Konrad Staines",

year = "2017",

month = apr,

day = "6",

doi = "10.1136/bcr-2016-218663",

language = "English",

volume = "2017",

journal = "BMJ Case Reports",

issn = "1757-790X",

publisher = "BMJ Publishing Group",

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TY - JOUR

T1 - Oral hairy leukoplakia arising in a patient with hairy cell leukaemia

T2 - the first reported case

AU - Davis, Gemma

AU - Perks, Alexandra

AU - Liyanage, Pemith

AU - Staines, Konrad

PY - 2017/4/6

Y1 - 2017/4/6

N2 - Oral hairy leukoplakia (OHL) is an oral mucosal lesion that is associated with Epstein-Barr virus infection. It commonly presents as an asymptomatic, non-removable white patch on the lateral borders of the tongue in individuals who are immunocompromised. Historically, OHL was thought to be pathognomonic of HIV infection; however, it is now an established phenomenon in a range of conditions affecting immune competence. Hairy cell leukaemia (HCL) is a rare chronic B cell lymphoproliferative disease named after the distinctive cytology of the atypical cells. We report the first case of OHL arising in an individual with HCL that resolved following remission of the haematological malignancy.

AB - Oral hairy leukoplakia (OHL) is an oral mucosal lesion that is associated with Epstein-Barr virus infection. It commonly presents as an asymptomatic, non-removable white patch on the lateral borders of the tongue in individuals who are immunocompromised. Historically, OHL was thought to be pathognomonic of HIV infection; however, it is now an established phenomenon in a range of conditions affecting immune competence. Hairy cell leukaemia (HCL) is a rare chronic B cell lymphoproliferative disease named after the distinctive cytology of the atypical cells. We report the first case of OHL arising in an individual with HCL that resolved following remission of the haematological malignancy.

KW - Epstein-Barr Virus Infections/complications

KW - Humans

KW - Leukemia, Hairy Cell/drug therapy

KW - Leukoplakia, Hairy/diagnosis

KW - Lichen Planus, Oral/diagnosis

KW - Male

KW - Middle Aged

KW - Purines

U2 - 10.1136/bcr-2016-218663

DO - 10.1136/bcr-2016-218663

M3 - Article (Academic Journal)

C2 - 28385698

SN - 1757-790X

VL - 2017

JO - BMJ Case Reports

JF - BMJ Case Reports

ER -

Oral hairy leukoplakia arising in a patient with hairy cell leukaemia: the first reported case

Abstract

Bibliographical note

UN SDGs

Keywords

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