Osteoprotegerin and B-type natriuretic peptide in acute coronary syndromes with preserved systolic function: Relation to coronary artery disease extension

A Palazzuoli, R Ascione, M Gallota, A Calabro, S Gonnelli, I Quatrini, MS Campagna, B Franci, R Nuti

Research output: Contribution to journalArticle (Academic Journal)

3 Citations (Scopus)

Abstract

OBJECTIVES: To analyze Osteoprotegerin (OPG), and BNP plasma levels in patients with non-ST elevation acute coronary syndrome (NSTE-ACS), in relation to clinical presentation and to coronary atherosclerosis diffusion. METHODS: 155 CAD patients were classified in four groups: stable angina (SA n=42), unstable angina (UA n=35) non-ST elevation myocardial infarction (NSTEMI n=45) and control group (n=33), measuring OPG and BNP at hospital admission. We compared both biomarkers in relation to the number of coronary narrowed vessels (1-,2-,3 or more vessels disease), and to the stenoses degree by Duke Jeopardy score. RESULTS: OPG levels were higher in patients with CAD respect to controls (p
Original languageEnglish
Pages (from-to)295-298
JournalInternational Journal of Cardiology
Volume137
Issue number3
DOIs
Publication statusPublished - 2009

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