Outcome Measures in Polymyalgia Rheumatica: A Systematic Review

Cátia Duarte, Ricardo Jorge de Oliveira Ferreira, Sarah Louise Mackie, John Richard Kirwan, José António Pereira da Silva

Research output: Contribution to journalArticle (Academic Journal)peer-review

10 Citations (Scopus)
214 Downloads (Pure)

Abstract

OBJECTIVE: To identify the instruments used to assess polymyalgia rheumatica (PMR) in published studies.

METHODS: A systematic literature review of clinical trials and longitudinal observational studies related to PMR, published from 1970 to 2014, was carried out. All outcome and assessment instruments were extracted and categorized according to core areas and domains, as defined by the OMERACT (Outcome Measures in Rheumatology) Filter 2.0.

RESULTS: Thirty-five articles (3221 patients) were included: 12 randomized controlled trials (RCT); 3 nonrandomized trials; and 20 observational studies. More than 20 domains were identified, measured by 29 different instruments. The most frequently used measures were pain, morning stiffness, patient global assessment and physician global assessment, erythrocyte sedimentation rate, and C-reactive protein. The definition of outcomes varied considerably between studies.

CONCLUSION: The outcome measures and instruments used in PMR are numerous and diversely defined. The establishment of a core set of validated and standardized outcome measurements is needed.

Original languageEnglish
Pages (from-to)2503-2511
Number of pages9
JournalJournal of Rheumatology
Volume42
Issue number12
Early online date15 Nov 2015
DOIs
Publication statusPublished - 1 Dec 2015

Keywords

  • polymyalgia rheumatica
  • outcome assessment
  • review literature
  • OMERACT

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