Oxygen supplementation before induction of general anaesthesia in horses

Hugo van Oostrom, Manon W H Schaap, J P A M van Loon

Research output: Contribution to journalArticle (Academic Journal)peer-review

3 Citations (Scopus)
328 Downloads (Pure)

Abstract

Reasons for performing study

Hypoventilation or apnoea, caused by the induction of general anaesthesia, may cause hypoxaemia. Preoxygenation may lengthen the period before this happens. No scientific studies are published on preoxygenation in equine anaesthesia.

Objectives

To determine whether supplementation of oxygen at a flow rate of 15 l/min for 3 min via a nasal cannula before induction of general anaesthesia is effective in elevating the arterial partial pressure of oxygen (PaO2) directly after induction.

Study design

Randomised, prospective clinical trial.

Methods

A total of 18 American Society of Anesthesiologists physical status 1 or 2 adult horses undergoing elective anaesthesia were randomly allocated to one of 2 groups. The first group (control) received no oxygen supplementation before induction of general anaesthesia, whereas the second group (oxygen) did. All horses were anaesthetised with intravenous detomidine, butorphanol, ketamine, midazolam and isoflurane. Directly after induction (T = 0) and 30 min later (T = 30) an arterial blood sample was taken for blood gas analysis. At T = 30 an estimate of intrapulmonary shunt fraction (Qs/Qt) was calculated.

Results

At T = 0 arterial partial pressure of oxygen (PaO2) was significantly higher in the oxygen group compared with the control group (11.0 ± 2.6 kPa vs. 7.4 ± 1.6 kPa; mean ± s.d., P = 0.005) and at T = 30 differences were not statistically significant. Partial pressure of carbon dioxide (PaCO2) and Qs/Qt did not differ between groups.

Conclusions

Supplementing oxygen by a nasal cannula before induction of general anaesthesia in horses is feasible and does effectively elevate the PaO2 immediately after induction. Future research is needed to determine whether supplementation of oxygen before induction of general anaesthesia in horses will affect outcomes.

Original languageEnglish
Pages (from-to)130-132
Number of pages3
JournalEquine Veterinary Journal
Volume49
Issue number1
Early online date25 Dec 2015
DOIs
Publication statusPublished - Jan 2017

Keywords

  • horse
  • preoxygenation
  • general anaesthesia
  • hypoxaemia
  • F shunt

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