Projects per year
We report efficient Pd-catalyzed cyclizations of oxime esters with 1,1-disubstituted alkenes as the basis of a general entry to alpha,alpha-disubstituted pyrrolidine derivatives. We also demonstrate that catalytic asymmetric variants of this chemistry are feasible by employing a suitable chiral ligand.
|Number of pages||3|
|Publication status||Published - 2013|
- KETONE O-PENTAFLUOROBENZOYLOXIMES
- HECK REACTIONS
- ENANTIOSELECTIVE SYNTHESIS
FingerprintDive into the research topics of 'Palladium catalyzed cyclizations of oxime esters with 1,1-disubstituted alkenes: synthesis of alpha,alpha-disubstituted dihydropyrroles and studies towards an asymmetric protocol'. Together they form a unique fingerprint.
- 2 Finished
3-month Core Capability for Chemistry Research
1/01/13 → 1/04/13
New Transition Metal Catalysed Methods for Alkyl C-N Bond Formation
Bower, J. F.
3/11/11 → 3/11/13