Palladium-Catalyzed ortho-Arylation of Carbamate-Protected Estrogens

Robin B Bedford, Peter B Brenner, Steven J Durrant, Timothy Gallagher, Carolina Méndez-Gálvez, Michelle Montgomery

Research output: Contribution to journalArticle (Academic Journal)peer-review

8 Citations (Scopus)
314 Downloads (Pure)

Abstract

The palladium-catalyzed ortho-arylation of diethylcarbamate-protected estrone and estriol with aryl iodides, gives the 2-arylated analogues. Subsequent removal of the carbamate directing group furnishes 2-arylated estrone, estradiol or estriol depending on the method used.
Original languageEnglish
Pages (from-to)3473–3478
Number of pages6
JournalJournal of Organic Chemistry
Volume81
Issue number9
Early online date8 Apr 2016
DOIs
Publication statusPublished - 6 May 2016

Structured keywords

  • BCS and TECS CDTs

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