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The palladium-catalyzed ortho-arylation of diethylcarbamate-protected estrone and estriol with aryl iodides, gives the 2-arylated analogues. Subsequent removal of the carbamate directing group furnishes 2-arylated estrone, estradiol or estriol depending on the method used.
|Number of pages||6|
|Journal||Journal of Organic Chemistry|
|Early online date||8 Apr 2016|
|Publication status||Published - 6 May 2016|
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