Skip to content

Paternal impact on the life course development of obesity and type 2 diabetes in the offspring

Research output: Contribution to journalReview article

Standard

Paternal impact on the life course development of obesity and type 2 diabetes in the offspring. / Sharp, Gemma C.; Lawlor, Debbie A.

In: Diabetologia, Vol. 62, No. 10, 01.10.2019, p. 1802-1810.

Research output: Contribution to journalReview article

Harvard

APA

Vancouver

Author

Bibtex

@article{b56bb419d36444839925b633e150bcca,
title = "Paternal impact on the life course development of obesity and type 2 diabetes in the offspring",
abstract = "The aetiologies of obesity and type 2 diabetes are incredibly complex, but the potential role of paternal influences remains relatively understudied. A better understanding of paternal influences on offspring risk of obesity and type 2 diabetes could have profound implications for public health, clinical practice and society. In this review, we outline potential biological and social mechanisms through which fathers might exert an impact on the health of their offspring. We also present a systematically compiled overview of the current evidence linking paternal factors to offspring development of obesity and type 2 diabetes throughout the life course. Although evidence is accumulating to support paternal associations with offspring outcomes, more high-quality research is needed to overcome specific methodological challenges and provide stronger causal evidence.",
keywords = "developmental origins of health and disease, epigenetics, fathers, life course development, obesity, paternal effects, review, type 2 diabetes",
author = "Sharp, {Gemma C.} and Lawlor, {Debbie A.}",
year = "2019",
month = "10",
day = "1",
doi = "10.1007/s00125-019-4919-9",
language = "English",
volume = "62",
pages = "1802--1810",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer Berlin Heidelberg",
number = "10",

}

RIS - suitable for import to EndNote

TY - JOUR

T1 - Paternal impact on the life course development of obesity and type 2 diabetes in the offspring

AU - Sharp, Gemma C.

AU - Lawlor, Debbie A.

PY - 2019/10/1

Y1 - 2019/10/1

N2 - The aetiologies of obesity and type 2 diabetes are incredibly complex, but the potential role of paternal influences remains relatively understudied. A better understanding of paternal influences on offspring risk of obesity and type 2 diabetes could have profound implications for public health, clinical practice and society. In this review, we outline potential biological and social mechanisms through which fathers might exert an impact on the health of their offspring. We also present a systematically compiled overview of the current evidence linking paternal factors to offspring development of obesity and type 2 diabetes throughout the life course. Although evidence is accumulating to support paternal associations with offspring outcomes, more high-quality research is needed to overcome specific methodological challenges and provide stronger causal evidence.

AB - The aetiologies of obesity and type 2 diabetes are incredibly complex, but the potential role of paternal influences remains relatively understudied. A better understanding of paternal influences on offspring risk of obesity and type 2 diabetes could have profound implications for public health, clinical practice and society. In this review, we outline potential biological and social mechanisms through which fathers might exert an impact on the health of their offspring. We also present a systematically compiled overview of the current evidence linking paternal factors to offspring development of obesity and type 2 diabetes throughout the life course. Although evidence is accumulating to support paternal associations with offspring outcomes, more high-quality research is needed to overcome specific methodological challenges and provide stronger causal evidence.

KW - developmental origins of health and disease

KW - epigenetics

KW - fathers

KW - life course development

KW - obesity

KW - paternal effects

KW - review

KW - type 2 diabetes

UR - http://www.scopus.com/inward/record.url?scp=85071452323&partnerID=8YFLogxK

U2 - 10.1007/s00125-019-4919-9

DO - 10.1007/s00125-019-4919-9

M3 - Review article

C2 - 31451867

AN - SCOPUS:85071452323

VL - 62

SP - 1802

EP - 1810

JO - Diabetologia

JF - Diabetologia

SN - 0012-186X

IS - 10

ER -