Patient centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children

Nigel, J Hall; Frances C Sherratt; Simon Eaton; Erin Walker; Maria Chorozoglou; Lucy Beasant; Michael P. Stanton; Harriet J Corbett; Dean  Rex; Natalie Hutchings; Elizabeth Dixon; Esther M Crawley; Jane Blazeby; Bridget Young; Isabel Reading

doi:10.1136/bmjpo-2022-001673

Patient centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children

Nigel, J Hall^*
, Frances C Sherratt
, Simon Eaton
, Erin Walker
, Maria Chorozoglou
, Lucy Beasant
, Michael P. Stanton
, Harriet J Corbett
, Dean Rex
, Natalie Hutchings
, Elizabeth Dixon
, Esther M Crawley
, Jane Blazeby
, Bridget Young
, Isabel Reading

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

9 Citations (Scopus)

Abstract

While non-operative treatment has emerged as an alternative to surgery for the treatment of uncomplicated acute appendicitis in children, comparative patient-centred outcomes are not well documented. We investigated these in a feasibility randomised trial. Of 57 randomised participants, data were available for 26. Compared with appendicectomy, children allocated to non-operative treatment reported higher short-term quality of life scores, shorter duration of requiring analgesia, more rapid return to normal activities and shorter parental absence from work. These preliminary data suggest differences exist in recovery profile and quality of life between these treatments that are important to measure in a larger RCT

Original language	English
Article number	e001673
Journal	BMJ Paediatrics Open
Volume	7
Issue number	1
DOIs	https://doi.org/10.1136/bmjpo-2022-001673
Publication status	Published - 6 Feb 2023

Bibliographical note

Funding Information:
The study was funded by the National Institute for Health Research Health Technology Assessment Program (ref: 14/192/90).

Publisher Copyright:
© 2023 Author(s). Published by BMJ.

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Hall, N. J., Sherratt, F. C., Eaton, S., Walker, E., Chorozoglou, M., Beasant, L., Stanton, M. P., Corbett, H. J., Rex, D., Hutchings, N., Dixon, E., Crawley, E. M., Blazeby, J., Young, B., & Reading, I. (2023). Patient centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children. BMJ Paediatrics Open, 7(1), Article e001673. https://doi.org/10.1136/bmjpo-2022-001673

@article{4f1e1744b179423787e248697bc40f86,

title = "Patient centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children",

abstract = "While non-operative treatment has emerged as an alternative to surgery for the treatment of uncomplicated acute appendicitis in children, comparative patient-centred outcomes are not well documented. We investigated these in a feasibility randomised trial. Of 57 randomised participants, data were available for 26. Compared with appendicectomy, children allocated to non-operative treatment reported higher short-term quality of life scores, shorter duration of requiring analgesia, more rapid return to normal activities and shorter parental absence from work. These preliminary data suggest differences exist in recovery profile and quality of life between these treatments that are important to measure in a larger RCT",

author = "Hall, \{Nigel, J\} and Sherratt, \{Frances C\} and Simon Eaton and Erin Walker and Maria Chorozoglou and Lucy Beasant and Stanton, \{Michael P.\} and Corbett, \{Harriet J\} and Dean Rex and Natalie Hutchings and Elizabeth Dixon and Crawley, \{Esther M\} and Jane Blazeby and Bridget Young and Isabel Reading",

note = "Funding Information: The study was funded by the National Institute for Health Research Health Technology Assessment Program (ref: 14/192/90). Publisher Copyright: {\textcopyright} 2023 Author(s). Published by BMJ.",

year = "2023",

month = feb,

day = "6",

doi = "10.1136/bmjpo-2022-001673",

language = "English",

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Hall, NJ, Sherratt, FC, Eaton, S, Walker, E, Chorozoglou, M, Beasant, L, Stanton, MP, Corbett, HJ, Rex, D, Hutchings, N, Dixon, E, Crawley, EM, Blazeby, J, Young, B & Reading, I 2023, 'Patient centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children', BMJ Paediatrics Open, vol. 7, no. 1, e001673. https://doi.org/10.1136/bmjpo-2022-001673

TY - JOUR

T1 - Patient centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children

AU - Hall, Nigel, J

AU - Sherratt, Frances C

AU - Eaton, Simon

AU - Walker, Erin

AU - Chorozoglou, Maria

AU - Beasant, Lucy

AU - Stanton, Michael P.

AU - Corbett, Harriet J

AU - Rex, Dean

AU - Hutchings, Natalie

AU - Dixon, Elizabeth

AU - Crawley, Esther M

AU - Blazeby, Jane

AU - Young, Bridget

AU - Reading, Isabel

N1 - Funding Information: The study was funded by the National Institute for Health Research Health Technology Assessment Program (ref: 14/192/90). Publisher Copyright: © 2023 Author(s). Published by BMJ.

PY - 2023/2/6

Y1 - 2023/2/6

N2 - While non-operative treatment has emerged as an alternative to surgery for the treatment of uncomplicated acute appendicitis in children, comparative patient-centred outcomes are not well documented. We investigated these in a feasibility randomised trial. Of 57 randomised participants, data were available for 26. Compared with appendicectomy, children allocated to non-operative treatment reported higher short-term quality of life scores, shorter duration of requiring analgesia, more rapid return to normal activities and shorter parental absence from work. These preliminary data suggest differences exist in recovery profile and quality of life between these treatments that are important to measure in a larger RCT

AB - While non-operative treatment has emerged as an alternative to surgery for the treatment of uncomplicated acute appendicitis in children, comparative patient-centred outcomes are not well documented. We investigated these in a feasibility randomised trial. Of 57 randomised participants, data were available for 26. Compared with appendicectomy, children allocated to non-operative treatment reported higher short-term quality of life scores, shorter duration of requiring analgesia, more rapid return to normal activities and shorter parental absence from work. These preliminary data suggest differences exist in recovery profile and quality of life between these treatments that are important to measure in a larger RCT

U2 - 10.1136/bmjpo-2022-001673

DO - 10.1136/bmjpo-2022-001673

M3 - Article (Academic Journal)

C2 - 36746524

SN - 2399-9772

VL - 7

JO - BMJ Paediatrics Open

JF - BMJ Paediatrics Open

IS - 1

M1 - e001673

ER -

Patient centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children

Abstract

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