Patient-Derived HIV-1 Nef Alleles Reveal Uncoupling of CD4 Downregulation and SERINC5 Antagonism Functions of the Viral Pathogenesis Factor

Benedikt Obermaier; Swetha Ananth; Nadine Tibroni; Virginia Pierini; Iart Luca Shytaj; Ricardo S Diaz; Marina Lusic; Oliver T Fackler

doi:10.1097/QAI.0000000000002418

Patient-Derived HIV-1 Nef Alleles Reveal Uncoupling of CD4 Downregulation and SERINC5 Antagonism Functions of the Viral Pathogenesis Factor

Benedikt Obermaier, Swetha Ananth, Nadine Tibroni, Virginia Pierini, Iart Luca Shytaj, Ricardo S Diaz, Marina Lusic, Oliver T Fackler

Research output: Contribution to journal › Article (Academic Journal) › peer-review

5 Citations (Scopus)

Original language	English
Pages (from-to)	e23-e26
Journal	Journal of Acquired Immune Deficiency Syndromes
Volume	85
Issue number	2
DOIs	https://doi.org/10.1097/QAI.0000000000002418
Publication status	Published - 1 Oct 2020

Keywords

Alleles
CD4 Antigens/genetics
Down-Regulation
HEK293 Cells
HIV Infections
HIV-1/genetics
Humans
Membrane Proteins/genetics
nef Gene Products, Human Immunodeficiency Virus/genetics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/QAI.0000000000002418

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Cite this

@article{57ea4aa8d09947b79092b6f0186de73f,

title = "Patient-Derived HIV-1 Nef Alleles Reveal Uncoupling of CD4 Downregulation and SERINC5 Antagonism Functions of the Viral Pathogenesis Factor",

keywords = "Alleles, CD4 Antigens/genetics, Down-Regulation, HEK293 Cells, HIV Infections, HIV-1/genetics, Humans, Membrane Proteins/genetics, nef Gene Products, Human Immunodeficiency Virus/genetics",

author = "Benedikt Obermaier and Swetha Ananth and Nadine Tibroni and Virginia Pierini and Shytaj, {Iart Luca} and Diaz, {Ricardo S} and Marina Lusic and Fackler, {Oliver T}",

year = "2020",

month = oct,

day = "1",

doi = "10.1097/QAI.0000000000002418",

language = "English",

volume = "85",

pages = "e23--e26",

journal = "Journal of Acquired Immune Deficiency Syndromes",

issn = "1525-4135",

publisher = "Lippincott Williams and Wilkins",

number = "2",

}

Patient-Derived HIV-1 Nef Alleles Reveal Uncoupling of CD4 Downregulation and SERINC5 Antagonism Functions of the Viral Pathogenesis Factor. / Obermaier, Benedikt; Ananth, Swetha; Tibroni, Nadine et al.
In: Journal of Acquired Immune Deficiency Syndromes, Vol. 85, No. 2, 01.10.2020, p. e23-e26.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

TY - JOUR

T1 - Patient-Derived HIV-1 Nef Alleles Reveal Uncoupling of CD4 Downregulation and SERINC5 Antagonism Functions of the Viral Pathogenesis Factor

AU - Obermaier, Benedikt

AU - Ananth, Swetha

AU - Tibroni, Nadine

AU - Pierini, Virginia

AU - Shytaj, Iart Luca

AU - Diaz, Ricardo S

AU - Lusic, Marina

AU - Fackler, Oliver T

PY - 2020/10/1

Y1 - 2020/10/1

KW - Alleles

KW - CD4 Antigens/genetics

KW - Down-Regulation

KW - HEK293 Cells

KW - HIV Infections

KW - HIV-1/genetics

KW - Humans

KW - Membrane Proteins/genetics

KW - nef Gene Products, Human Immunodeficiency Virus/genetics

U2 - 10.1097/QAI.0000000000002418

DO - 10.1097/QAI.0000000000002418

M3 - Article (Academic Journal)

C2 - 32541384

SN - 1525-4135

VL - 85

SP - e23-e26

JO - Journal of Acquired Immune Deficiency Syndromes

JF - Journal of Acquired Immune Deficiency Syndromes

IS - 2

ER -