Pelvic inflammatory disease and salpingitis: incidence of primary and repeat episodes in England

Michael J Price*, A E Ades, Nicky J Welton, I Simms, Paul J Horner

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)

6 Citations (Scopus)
247 Downloads (Pure)

Abstract

Pelvic inflammatory disease (PID) and more specifically salpingitis (visually confirmed inflammation) is the primary cause of tubal factor infertility and is an important risk factor for ectopic pregnancy. The risk of these outcomes increases following repeated episodes of PID. We developed a homogenous discrete-time Markov model for the distribution of PID history in the UK. We used a Bayesian framework to fully propagate parameter uncertainty into the model outputs. We estimated the model parameters from routine data, prospective studies, and other sources. We estimated that for women aged 35–44 years, 33·6% and 16·1% have experienced at least one episode of PID and salpingitis, respectively (diagnosed or not) and 10·7% have experienced one salpingitis and no further PID episodes, 3·7% one salpingitis and one further PID episode, and 1·7% one salpingitis and ⩾2 further PID episodes. Results are consistent with numerous external data sources, but not all. Studies of the proportion of PID that is diagnosed, and the proportion of PIDs that are salpingitis together with the severity distribution in different diagnostic settings and of overlap between routine data sources of PID would be valuable.

Original languageEnglish
Pages (from-to)208-215
Number of pages8
JournalEpidemiology and Infection
Volume145
Issue number1
Early online date28 Sep 2016
DOIs
Publication statusPublished - Jan 2017

Keywords

  • Cumulative incidence
  • incidence
  • Markov model
  • pelvic inflammatory disease (PID)
  • repeat PID

Fingerprint Dive into the research topics of 'Pelvic inflammatory disease and salpingitis: incidence of primary and repeat episodes in England'. Together they form a unique fingerprint.

  • Projects

    CHLAMYDIA SYNTHESIS

    Ades, A. E.

    1/07/091/01/12

    Project: Research

    Cite this