Penicillanic Acid Sulfones Inactivate the Extended-Spectrum β-Lactamase CTX-M-15 through Formation of a Serine-Lysine Cross-Link: An Alternative Mechanism of β-Lactamase Inhibition

Philip Hinchliffe, Catherine L Tooke, Christopher R Bethel, Benlian Wang, Chris Arthur, Kate J Heesom, Stuart Shapiro, Daniela M. Schlatzer, Krisztina M Papp-Wallace, Robert A. Bonomo*, James Spencer*

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

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Chemistry

Biochemistry, Genetics and Molecular Biology

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Immunology and Microbiology