Peroxisome protein import: some answers, more questions

Alison Baker, Imogen Averil Sparkes

Research output: Contribution to journalReview article (Academic Journal)peer-review

52 Citations (Scopus)


Recent advances in the study of plant peroxisomes are shedding new light on the importance of these organelles for plant development, and are revealing similarities and differences in peroxisome protein import pathways between plants, animals and fungi. For example, the import of matrix proteins that carry the PTS1 and PTS2 targeting signals is coupled in plants as it is in mammals, whereas these import pathways are separate in fungi. The expression of a human peroxisomal ATPase partially rescues the equivalent Arabidopsis mutant. Ubiquitination might play a role in receptor recycling in Saccharomyces cerevisiae and exciting progress is being made through studies of the targeting of membrane proteins.

Original languageEnglish
Pages (from-to)640-7
Number of pages8
JournalCurrent Opinion in Plant Biology
Issue number6
Publication statusPublished - Dec 2005


  • Arabidopsis
  • Arabidopsis Proteins
  • Intracellular Membranes
  • Peroxisomes
  • Protein Transport
  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Review


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