Phosphoinositides and the regulation of tubular-based endosomal sorting

Research output: Contribution to journalArticle (Academic Journal)peer-review

10 Citations (Scopus)

Abstract

From the pioneering work of Mabel and Lowell Hokin in the 1950s, the biology of this specific isomer of hexahydroxycyclohexane and its phosphorylated derivatives, in the form of inositol phosphates and phosphoinositides, has expanded to fill virtually every corner of cell biology, whole-organism physiology and development. In the present paper, I give a personal view of the role played by phosphoinositides in regulating the function of the endosomal network, and, in so doing, highlight some of the basic properties through which phosphoinositides regulate cell function.
Translated title of the contributionPhosphoinositides and the regulation of tubular-based endosomal sorting
Original languageEnglish
Pages (from-to)839 - 850
Number of pages12
JournalBiochemical Society Transactions
Volume39 (4)
DOIs
Publication statusPublished - Aug 2011

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