Photodynamic therapy in the management of lesions of the head and neck

Ben Green, Alistair R M Cobb, Colin Hopper

Research output: Contribution to journalArticle (Academic Journal)peer-review

24 Citations (Scopus)

Abstract

Photodynamic therapy (PDT) is a promising and effective treatment for lesions of the head and neck. It uses illumination with light of a specific wavelength, which activates a photosensitising drug in the presence of oxygen. It can be used in combination with other treatments or on its own, and results in the cellular destruction of the lesion through a free-radical process. Photosensitisers can be applied topically or given systemically depending on the lesion being treated. Results indicate that PDT is an effective adjunct to standard conventional treatments. We review its use.

Original languageEnglish
Pages (from-to)283-7
Number of pages5
JournalBritish Journal of Oral and Maxillofacial Surgery
Volume51
Issue number4
DOIs
Publication statusPublished - Jun 2013

Bibliographical note

Copyright © 2012 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

Keywords

  • Free Radicals
  • Head and Neck Neoplasms
  • Humans
  • Mouth Neoplasms
  • Neoadjuvant Therapy
  • Photochemotherapy
  • Photosensitizing Agents
  • Precancerous Conditions

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