Photodynamic therapy in the management of lesions of the head and neck

Ben Green; Alistair R M Cobb; Colin Hopper

doi:10.1016/j.bjoms.2012.11.011

Photodynamic therapy in the management of lesions of the head and neck

Ben Green, Alistair R M Cobb, Colin Hopper

Bristol Dental School

Research output: Contribution to journal › Article (Academic Journal) › peer-review

24 Citations (Scopus)

Abstract

Photodynamic therapy (PDT) is a promising and effective treatment for lesions of the head and neck. It uses illumination with light of a specific wavelength, which activates a photosensitising drug in the presence of oxygen. It can be used in combination with other treatments or on its own, and results in the cellular destruction of the lesion through a free-radical process. Photosensitisers can be applied topically or given systemically depending on the lesion being treated. Results indicate that PDT is an effective adjunct to standard conventional treatments. We review its use.

Original language	English
Pages (from-to)	283-7
Number of pages	5
Journal	British Journal of Oral and Maxillofacial Surgery
Volume	51
Issue number	4
DOIs	https://doi.org/10.1016/j.bjoms.2012.11.011
Publication status	Published - Jun 2013

Bibliographical note

Keywords

Free Radicals
Head and Neck Neoplasms
Humans
Mouth Neoplasms
Neoadjuvant Therapy
Photochemotherapy
Photosensitizing Agents
Precancerous Conditions

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title = "Photodynamic therapy in the management of lesions of the head and neck",

abstract = "Photodynamic therapy (PDT) is a promising and effective treatment for lesions of the head and neck. It uses illumination with light of a specific wavelength, which activates a photosensitising drug in the presence of oxygen. It can be used in combination with other treatments or on its own, and results in the cellular destruction of the lesion through a free-radical process. Photosensitisers can be applied topically or given systemically depending on the lesion being treated. Results indicate that PDT is an effective adjunct to standard conventional treatments. We review its use.",

keywords = "Free Radicals, Head and Neck Neoplasms, Humans, Mouth Neoplasms, Neoadjuvant Therapy, Photochemotherapy, Photosensitizing Agents, Precancerous Conditions",

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T1 - Photodynamic therapy in the management of lesions of the head and neck

AU - Green, Ben

AU - Cobb, Alistair R M

AU - Hopper, Colin

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N2 - Photodynamic therapy (PDT) is a promising and effective treatment for lesions of the head and neck. It uses illumination with light of a specific wavelength, which activates a photosensitising drug in the presence of oxygen. It can be used in combination with other treatments or on its own, and results in the cellular destruction of the lesion through a free-radical process. Photosensitisers can be applied topically or given systemically depending on the lesion being treated. Results indicate that PDT is an effective adjunct to standard conventional treatments. We review its use.

AB - Photodynamic therapy (PDT) is a promising and effective treatment for lesions of the head and neck. It uses illumination with light of a specific wavelength, which activates a photosensitising drug in the presence of oxygen. It can be used in combination with other treatments or on its own, and results in the cellular destruction of the lesion through a free-radical process. Photosensitisers can be applied topically or given systemically depending on the lesion being treated. Results indicate that PDT is an effective adjunct to standard conventional treatments. We review its use.

KW - Free Radicals

KW - Head and Neck Neoplasms

KW - Humans

KW - Mouth Neoplasms

KW - Neoadjuvant Therapy

KW - Photochemotherapy

KW - Photosensitizing Agents

KW - Precancerous Conditions

U2 - 10.1016/j.bjoms.2012.11.011

DO - 10.1016/j.bjoms.2012.11.011

M3 - Article (Academic Journal)

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VL - 51

SP - 283

EP - 287

JO - British Journal of Oral and Maxillofacial Surgery

JF - British Journal of Oral and Maxillofacial Surgery

SN - 0266-4356

IS - 4

ER -