Platelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4-deficient platelets

Matthew T Harper; Marion T van den Bosch; Ingeborg Hers; Alastair W Poole

doi:10.1182/blood-2014-12-618439

Platelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4-deficient platelets

Matthew T Harper, Marion T van den Bosch, Ingeborg Hers, Alastair W Poole

Research output: Contribution to journal › Article (Academic Journal) › peer-review

28 Citations (Scopus)

Original language	English
Pages (from-to)	3034-6
Number of pages	3
Journal	Blood
Volume	125
Issue number	19
DOIs	https://doi.org/10.1182/blood-2014-12-618439
Publication status	Published - 7 May 2015

Keywords

Adenosine Diphosphate
Animals
Blood Platelets
Cytoplasmic Granules
Exocytosis
Membrane Proteins
Mice
Mice, Knockout
Platelet Aggregation
Platelet Factor 4
Receptors, Purinergic P2Y12
Secretory Vesicles
Signal Transduction
Thromboxane A2

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10.1182/blood-2014-12-618439

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Professor Ingeborg Hers
- I.Hersbristol.acuk
- Bristol Doctoral College - Academic Director (PGR Strategic Partnerships)
- Bristol Medical School (THS) - Professor of Pharmacology and Cell Signalling
Person: Academic

Cite this

@article{c909d06c989043358f7dc9aecb900e21,

title = "Platelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4-deficient platelets",

keywords = "Adenosine Diphosphate, Animals, Blood Platelets, Cytoplasmic Granules, Exocytosis, Membrane Proteins, Mice, Mice, Knockout, Platelet Aggregation, Platelet Factor 4, Receptors, Purinergic P2Y12, Secretory Vesicles, Signal Transduction, Thromboxane A2",

author = "Harper, \{Matthew T\} and \{van den Bosch\}, \{Marion T\} and Ingeborg Hers and Poole, \{Alastair W\}",

year = "2015",

month = may,

day = "7",

doi = "10.1182/blood-2014-12-618439",

language = "English",

volume = "125",

pages = "3034--6",

journal = "Blood",

issn = "0006-4971",

publisher = "Elsevier B.V.",

number = "19",

}

TY - JOUR

T1 - Platelet dense granule secretion defects may obscure α-granule secretion mechanisms

T2 - evidence from Munc13-4-deficient platelets

AU - Harper, Matthew T

AU - van den Bosch, Marion T

AU - Hers, Ingeborg

AU - Poole, Alastair W

PY - 2015/5/7

Y1 - 2015/5/7

KW - Adenosine Diphosphate

KW - Animals

KW - Blood Platelets

KW - Cytoplasmic Granules

KW - Exocytosis

KW - Membrane Proteins

KW - Mice

KW - Mice, Knockout

KW - Platelet Aggregation

KW - Platelet Factor 4

KW - Receptors, Purinergic P2Y12

KW - Secretory Vesicles

KW - Signal Transduction

KW - Thromboxane A2

U2 - 10.1182/blood-2014-12-618439

DO - 10.1182/blood-2014-12-618439

M3 - Article (Academic Journal)

C2 - 25953980

SN - 0006-4971

VL - 125

SP - 3034

EP - 3036

JO - Blood

JF - Blood

IS - 19

ER -

Platelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4-deficient platelets

Keywords

Access to Document

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Profiles

Professor Ingeborg Hers

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