Pleiotropy-guided transcriptome imputation from normal and tumor tissues identifies candidate susceptibility genes for breast and ovarian cancer

Siddhartha Kar

Research output: Contribution to journalArticle (Academic Journal)peer-review

11 Citations (Scopus)
49 Downloads (Pure)
Original languageEnglish
Article number100042
JournalHuman Genetics and Genomics Advances
Volume2
Issue number3
DOIs
Publication statusPublished - 8 Jul 2021

Bibliographical note

Funding Information:
The analyses presented in this manuscript were funded by grant number R01CA211574 from the United States National Institutes of Health/National Cancer Institute. The GTEx Project was supported by the Common Fund of the Office of the Director of the National Institutes of Health, and by NCI, NHGRI, NHLBI, NIDA, NIMH, and NINDS. The results published here are in part based upon data generated by TCGA Research Network. The BCAC breast cancer genome-wide association analyses were supported by the Government of Canada through Genome Canada and the Canadian Institutes of Health Research, the Minist?re de l??conomie, de la Science et de l'Innovation du Qu?bec through G?nome Qu?bec and grant PSR-SIIRI-701, the National Institutes of Health (U19 CA148065 and X01HG007492), Cancer Research UK (C1287/A10118, C1287/A16563, and C1287/A10710) and the European Union (HEALTH-F2-2009-223175, H2020 633784, and 634935). All studies and funders are listed in Michailidou et al.22 The OCAC ovarian cancer genome-wide association meta-analyses were supported by the US National Institutes of Health (CA1X01HG007491-01 [C.I.A.], U19-CA148112 [T.A.S.], R01-CA149429 [C.M.P.], and R01-CA058598 [M.T.G.]); Canadian Institutes of Health Research (MOP-86727 [L.E.K.]), and the Ovarian Cancer Research Fund (A.B.). The COGS project was funded through a European Commission's Seventh Framework Programme grant (agreement number 223175: HEALTH-F2?2009-223175). All studies and funders are listed in Phelan et al.23, The authors declare no competing interests.

Funding Information:
The analyses presented in this manuscript were funded by grant number R01CA211574 from the United States National Institutes of Health/National Cancer Institute . The GTEx Project was supported by the Common Fund of the Office of the Director of the National Institutes of Health , and by NCI , NHGRI , NHLBI , NIDA , NIMH , and NINDS . The results published here are in part based upon data generated by TCGA Research Network. The BCAC breast cancer genome-wide association analyses were supported by the Government of Canada through Genome Canada and the Canadian Institutes of Health Research , the Ministère de l’Économie, de la Science et de l’Innovation du Québec through Génome Québec and grant PSR-SIIRI-701 , the National Institutes of Health ( U19 CA148065 and X01HG007492 ), Cancer Research UK ( C1287/A10118 , C1287/A16563 , and C1287/A10710 ) and the European Union ( HEALTH-F2-2009-223175 , H2020 633784 , and 634935 ). All studies and funders are listed in Michailidou et al. 22 The OCAC ovarian cancer genome-wide association meta-analyses were supported by the US National Institutes of Health ( CA1X01HG007491-01 [C.I.A.], U19-CA148112 [T.A.S.], R01-CA149429 [C.M.P.], and R01-CA058598 [M.T.G.]); Canadian Institutes of Health Research ( MOP-86727 [L.E.K.]), and the Ovarian Cancer Research Fund (A.B.). The COGS project was funded through a European Commission’s Seventh Framework Programme grant (agreement number 223175: HEALTH-F2–2009-223175 ). All studies and funders are listed in Phelan et al. 23

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© 2021 The Author(s)

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