Abstract
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women, associated with a characteristic ovarian appearance at ultrasound scan, hyperandrogenism, and ovulatory disorders. The pathogenesis appears to be mainly related to reduced insulin sensitivity in peripheral tissues, leading to hyperinsulinaemia. There is a wide variation in the severity of PCOS symptoms. Women with PCOS are believed to be predisposed to a variety of complications in pregnancy. We present a summary of the evidence surrounding these claims and discuss the weaknesses of the available to date studies.
| Original language | English |
|---|---|
| Pages (from-to) | 922-932 |
| Number of pages | 11 |
| Journal | BJOG: An International Journal of Obstetrics and Gynaecology |
| Volume | 114 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Aug 2007 |
Keywords
- GESTATIONAL DIABETES-MELLITUS
- INSULIN-RESISTANCE
- insulin
- MIDDLE-AGED WOMEN
- outcome
- IMPAIRED GLUCOSE-TOLERANCE
- ACTIVATOR INHIBITOR ACTIVITY
- FACTOR-BINDING PROTEIN-1
- PCOS
- pregnancy
- SERUM LUTEINIZING-HORMONE
- IN-VITRO FERTILIZATION
- C-REACTIVE PROTEIN
- EPL
- GRADE CHRONIC INFLAMMATION