Pore-forming small molecules offer a promising way to tackle cystic fibrosis.

David N Sheppard; Anthony P Davis

doi:10.1038/d41586-019-00781-y

Pore-forming small molecules offer a promising way to tackle cystic fibrosis.

David N Sheppard, Anthony P Davis

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Abstract

In cystic fibrosis, ion-transport abnormalities cause problems in many organs. A small molecule that forms cell-membrane pores which allow ion transport, shows promise in studies of human cells and an animal model of the disease. See Letter p. 405.

Original language	English
Pages (from-to)	315-317
Number of pages	3
Journal	Nature
Volume	567
Issue number	7748
Early online date	13 Mar 2019
DOIs	https://doi.org/10.1038/d41586-019-00781-y
Publication status	Published - 21 Mar 2019

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10.1038/d41586-019-00781-y

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title = "Pore-forming small molecules offer a promising way to tackle cystic fibrosis.",

abstract = "In cystic fibrosis, ion-transport abnormalities cause problems in many organs. A small molecule that forms cell-membrane pores which allow ion transport, shows promise in studies of human cells and an animal model of the disease. See Letter p. 405.",

author = "Sheppard, {David N} and Davis, {Anthony P}",

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AU - Sheppard, David N

AU - Davis, Anthony P

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N2 - In cystic fibrosis, ion-transport abnormalities cause problems in many organs. A small molecule that forms cell-membrane pores which allow ion transport, shows promise in studies of human cells and an animal model of the disease. See Letter p. 405.

AB - In cystic fibrosis, ion-transport abnormalities cause problems in many organs. A small molecule that forms cell-membrane pores which allow ion transport, shows promise in studies of human cells and an animal model of the disease. See Letter p. 405.

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DO - 10.1038/d41586-019-00781-y

M3 - Article (Academic Journal)

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VL - 567

SP - 315

EP - 317

JO - Nature

JF - Nature

IS - 7748

ER -

Pore-forming small molecules offer a promising way to tackle cystic fibrosis.

Abstract

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