Possible novel targets for therapeutic angiogenesis

B Cristofaro, C Emanueli

Research output: Contribution to journalArticle (Academic Journal)peer-review

34 Citations (Scopus)


An increasing number of studies about the molecular basis of angiogenesis are rapidly disclosing novel signal pathways involved in the blood vessel formation process. This review will focus on bone morphogenic proteins, Hedgehog, Notch, ephrins, neuropilins, neurotrophins and netrins. These recently discovered angiogenesis mediators are involved in vascular development during embryogenesis and, interestingly, they are shared between the nervous and vascular systems. They represent new potential targets in the vasculature and suggest novel therapeutic opportunities.
Translated title of the contributionPossible novel targets for therapeutic angiogenesis
Original languageEnglish
Pages (from-to)102 - 108
Number of pages7
JournalCurrent Opinion in Pharmacology
Publication statusPublished - Apr 2009

Bibliographical note

Publisher: Elsevier

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